Key features and details
- Selective σ1 antagonist
- CAS Number: 193527-91-2
- Purity: > 99%
- Soluble in ethanol to 10 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameIPAG (1-(4-iodophenyl)-3-(2-adamantyl)guanidine), sigma1 antagonist
DescriptionSelective σ1 antagonist
Selective σ1 antagonist (Ki = 8 μM). Shows GTP- and suramin-sensitive affinity binding. Induces cell death and inhibits tumor growth. Active in vitro and in vivo.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in ethanol to 10 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146440 has not yet been referenced specifically in any publications.