Overview

  • Product name

    Anti-IPPK/IPK1 antibody
  • Description

    Rabbit polyclonal to IPPK/IPK1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human IPPK/IPK1 (internal sequence).
    Database link: Q9H8X2

  • Positive control

    • RAW, K562, LOVO and 3T3 cell extracts. Human brain tissue. HepG2 cells.
  • General notes

     This product was previously labelled as IPPK

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.4
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 50% Glycerol, 0.87% Sodium chloride

    PBS without Mg2+ and Ca2+.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab196781 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 56 kDa.
ICC/IF 1/100 - 1/500.
IHC-P 1/50 - 1/100.

Target

  • Function

    Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). InsP6 is involved in many processes such as mRNA export, non-homologous end-joining, endocytosis, ion channel regulation. It also protects cells from TNF-alpha-induced apoptosis.
  • Tissue specificity

    Ubiquitously expressed, with high expression in heart, brain, testis and placenta.
  • Sequence similarities

    Belongs to the IPK1 type 2 family.
  • Domain

    The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.
  • Cellular localization

    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • 3 antibody
    • 4 antibody
    • 5 antibody
    • 6)P5 2-kinase antibody
    • 6-pentakisphosphate 2-kinase antibody
    • bA476B13.1 (novel protein) antibody
    • bA476B13.1 antibody
    • C9orf12 antibody
    • inositol 1,3,4,5,6 pentakisphosphate 2 kinase antibody
    • Inositol pentakisphosphate 2 kinase antibody
    • Inositol-1 antibody
    • Inositol-pentakisphosphate 2-kinase antibody
    • Ins antibody
    • Ins(1 antibody
    • Ins(1,3,4,5,6)P5 2 kinase antibody
    • InsP5 2 kinase antibody
    • InsP5 2-kinase antibody
    • INSP5K2 antibody
    • IP5K antibody
    • IPK1 antibody
    • IPK1 homolog antibody
    • IPPK antibody
    • IPPK_HUMAN antibody
    see all

Images

  • All lanes : Anti-IPPK/IPK1 antibody (ab196781) at 1/500 dilution

    Lane 1 : RAW cell extracts
    Lane 2 : K562 cell extracts
    Lane 3 : LOVO cell extracts
    Lane 4 : 3T3 cell extract
    Lane 5 : Cell extracts with synthesized peptide

    Predicted band size: 56 kDa

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling IPPK/IPK1 with ab196781 at 1/50 dilution. The image on the right is pre-incubated with synthesized peptide.

  • Immunofluorescent analysis of HepG2 cells labeling IPPK/IPK1 with ab196781 at 1/100 dilution. The image on the right is pre-incubated with synthesized peptide.

References

ab196781 has not yet been referenced specifically in any publications.

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