Overview

  • Product name

    IQ-1S, JNK3 inhibitor
  • Description

    Selective JNK3 inhibitor
  • Biological description

    Selective JNK3 inhibitor (IC50 values are 390, 360 and 87 nM for JNK1, 2 and 3 respectively). Inhibits JNK phosphorylation and NFκB /AP-1 transcriptional activity. Shows immunosuppressant effects in vivo.
  • CAS Number

    23146-22-7
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Schepetkin IA  et al. Anti-Inflammatory Effects and Joint Protection in Collagen-Induced Arthritis after Treatment with IQ-1S, a Selective c-Jun N-Terminal Kinase Inhibitor. J Pharmacol Exp Ther 353:505-16 (2015). Read more (PubMed: 25784649) »

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