Key features and details
- Cell-permeable STAT5 inhibitor
- CAS Number: 401463-02-3
- Purity: > 98%
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameIQDMA, Cell-permeable STAT5 inhibitor
DescriptionCell-permeable STAT5 inhibitor
Cell-permeable STAT5 inhibitor (IC50 = 8 μM). Indoloquinoline derivative. Antineoplastic agent with broad spectrum antitumor activity seen in vitro. Induces cell-cycle arrest at the G2/M phase.
Storage instructionsStore at +4°C. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 100 mM and in ethanol to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141192 has been referenced in 1 publication.
- Itcho K et al. Angiotensin 1-7 suppresses angiotensin II mediated aldosterone production via JAK/STAT signaling inhibition. J Steroid Biochem Mol Biol 185:137-141 (2019). PubMed: 30125658