Anti-IRAK2 antibody - C-terminal (ab191027)
Key features and details
- Rabbit polyclonal to IRAK2 - C-terminal
- Suitable for: WB, IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-IRAK2 antibody - C-terminal
See all IRAK2 primary antibodies -
Description
Rabbit polyclonal to IRAK2 - C-terminal -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Rat, Human
Predicted to work with: Cow, Orangutan -
Immunogen
Synthetic peptide corresponding to Human IRAK2 aa 600 to the C-terminus (C terminal).
Database link: O43187 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Preservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab191027 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 69 kDa.
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IHC-P |
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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WB
Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 69 kDa. |
IHC-P
Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. -
Tissue specificity
Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes. -
Sequence similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Contains 1 death domain.
Contains 1 protein kinase domain. -
Domain
The protein kinase domain is predicted to be catalytically inactive. - Information by UniProt
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Database links
- Entrez Gene: 515034 Cow
- Entrez Gene: 3656 Human
- Entrez Gene: 362418 Rat
- Omim: 603304 Human
- SwissProt: Q0P5I2 Cow
- SwissProt: O43187 Human
- SwissProt: Q5R810 Orangutan
- SwissProt: Q4QQS0 Rat
see all -
Alternative names
- il1rak2 antibody
- Interleukin 1 receptor associated kinase 2 antibody
- Interleukin 1 receptor associated kinase like 2 antibody
see all
Images
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All lanes : Anti-IRAK2 antibody - C-terminal (ab191027) at 0.5 µg/ml
Lane 1 : 22RV cell lysate
Lane 2 : A549 cell lysate
Lane 3 : PANC cell lysate
Lane 4 : SMMC cell lysate
Predicted band size: 69 kDa -
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue labeling IRAK2 with ab191027 at 1 µg/ml.
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Immunohistochemical analysis of paraffin-embedded Rat spleen tissue labeling IRAK2 with ab191027 at 1 µg/ml.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab191027 has not yet been referenced specifically in any publications.