Overview

  • Product name

    Irbesartan, AT1 receptor antagonist
  • Description

    Selective, competitive AT1 receptor antagonist
  • Biological description

    Selective, competitive AT1 receptor antagonist. Reduces vasopressin and aldosterone secretion. Shows vasodilatory and antihypertensive effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    138402-11-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Ibrahim MA  et al. Montelukast and irbesartan ameliorate metabolic and hepatic disorders in fructose-induced metabolic syndrome in rats. Eur J Pharmacol 724:204-10 (2014). Read more (PubMed: 24370493) »
  • Zhao Y  et al. Suppressive effects of irbesartan on inflammation and apoptosis in atherosclerotic plaques of apoE-/- mice: molecular imaging with 14C-FDG and 99mTc-annexin A5. PLoS One 9:e89338 (2014). Read more (PubMed: 24586699) »
  • Patel VB  et al. Angiotensin-converting enzyme 2 is a critical determinant of angiotensin II-induced loss of vascular smooth muscle cells and adverse vascular remodeling. Hypertension 64:157-64 (2014). Read more (PubMed: 24799609) »

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