Overview

  • Product name

  • Description

    Rabbit polyclonal to IRBIT
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human IRBIT aa 31-260.
    Database link: O43865

  • Positive control

    • IHC-P: Human breast cancer and kidney tissues.
  • General notes

    Protein previously labeled as AHCYL1.

Properties

Applications

Our Abpromise guarantee covers the use of ab238488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/20 - 1/200.

Target

  • Tissue specificity

    Expressed in dendritic cells.
  • Pathway

    Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.
  • Sequence similarities

    Belongs to the adenosylhomocysteinase family.
  • Developmental stage

    Expression increases markedly during activation of blood and skin DC (Langerhans cells), but is diminished in terminally differentiated tonsil DC.
  • Domain

    The PEST region is essential for the interaction with ITPR1. The PDZ-binding region is required for maximal interaction with ITPR1 and is also responsible for the IP3-insensitive interaction with ITPR1.
  • Cellular localization

    Endoplasmic reticulum.
  • Information by UniProt
  • Database links

  • Alternative names

    • AA409031 antibody
    • AdoHcyase 2 antibody
    • Ahcy-rs3 antibody
    • AHCYL1 antibody
    • DC expressed AHCY like molecule antibody
    • DC-expressed AHCY-like molecule antibody
    • DCAL antibody
    • Dendritic cell expressed AHCY like protein antibody
    • Inositol 1,4,5-trisphosphate receptor-binding protein antibody
    • IP3R binding protein released with inositol 1,4,5-trisphosphate antibody
    • IRBIT antibody
    • PRO0233 antibody
    • Putative adenosylhomocysteinase 2 antibody
    • S adenosyl L homocysteine hydrolase 2 antibody
    • S adenosylhomocysteine hydrolase like 1 antibody
    • S-adenosyl-L-homocysteine hydrolase 2 antibody
    • S-adenosylhomocysteine hydrolase-like protein 1 antibody
    • SAHH2_HUMAN antibody
    • XPVKONA antibody
    see all

Images

  • Paraffin-embedded human breast cancer tissue stained for IRBIT using ab238488 at 1/100 dilution in immunohistochemical analysis.

  • Paraffin-embedded human kidney tissue stained for IRBIT using ab238488 at 1/100 dilution in immunohistochemical analysis.

References

ab238488 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab238488.
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