Anti-IRF5 antibody - ChIP Grade (ab2932)

Goat polyclonal IRF5 antibody. Validated in WB, IP, IHC, ChIP and tested in Dog, Human. Cited in 13 publication(s). Independently reviewed in 4 review(s). Immunogen corresponding to synthetic peptide.

Publishing research using ab2932? Please let us know so that we can cite the reference in this datasheet.

ab2932 has been referenced in 13 publications.

  • Rodríguez M  et al. Fungal pattern receptors down-regulate the inflammatory response by a cross-inhibitory mechanism independent of interleukin-10 production. Immunology 150:184-198 (2017). PubMed: 27709605
  • Li D  et al. Specific detection of interferon regulatory factor 5 (IRF5): A case of antibody inequality. Sci Rep 6:31002 (2016). PubMed: 27481535
  • Massimino M  et al. IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation. Carcinogenesis 35:1132-43 (2014). Human . PubMed: 24445143
  • McEwan WA  et al. Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21. Nat Immunol 14:327-36 (2013). PubMed: 23455675
  • Stein MF  et al. Multiple interferon regulatory factor and NF-?B sites cooperate in mediating cell-type- and maturation-specific activation of the human CD83 promoter in dendritic cells. Mol Cell Biol 33:1331-44 (2013). PubMed: 23339870
  • Negishi H  et al. Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nat Immunol 13:659-66 (2012). PubMed: 22610141
  • Krausgruber T  et al. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol 12:231-8 (2011). WB ; Human . PubMed: 21240265
  • Krausgruber T  et al. IRF5 is required for late-phase TNF secretion by human dendritic cells. Blood 115:4421-30 (2010). WB, ChIP, IP ; Human . PubMed: 20237317
  • Feng D  et al. Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression. J Immunol 185:6003-12 (2010). IP ; Human . PubMed: 20935208
  • Hu G & Barnes BJ IRF-5 is a mediator of the death receptor-induced apoptotic signaling pathway. J Biol Chem 284:2767-77 (2009). WB, ChIP, IP ; Human . PubMed: 19028697
  • Ye L  et al. Methamphetamine enhances Hepatitis C virus replication in human hepatocytes. J Viral Hepat 15:261-70 (2008). WB ; Human . PubMed: 18307590
  • Graham RR  et al. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus. Proc Natl Acad Sci U S A 104:6758-63 (2007). WB ; Human . PubMed: 17412832
  • Ning S  et al. Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit. J Virol 79:11671-6 (2005). PubMed: 16140744


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