Overview

  • Product name

    Anti-Iroquois homeobox protein 3/IRX3 antibody
    See all Iroquois homeobox protein 3/IRX3 primary antibodies
  • Description

    Rabbit polyclonal to Iroquois homeobox protein 3/IRX3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide within Human Iroquois homeobox protein 3/IRX3 aa 445-490 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    PAAAAA FARPAEPEGG TDRCSALEVE KKLLKTAFQP VPRRPQNHLD


    Database link: P78415

  • Positive control

    • IHC-P: Mouse brain lysates.
  • General notes

     This product was previously labelled as Iroquois homeobox protein 3

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 1% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab217954 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 52 kDa.

Target

  • Function

    Transcription factor. Involved in SHH-dependent neural patterning. Together with NKX2-2 and NKX6-1 acts to restrict the generation of motor neurons to the appropriate region of the neural tube. Belongs to the class I proteins of neuronal progenitor factors, which are repressed by SHH signals. Involved in the transcriptional repression of MNX1 in non-motor neuron cells.
  • Sequence similarities

    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • AI894186 antibody
    • Homeodomain protein IRXB1 antibody
    • Iroquois class homeodomain protein IRX 1 antibody
    • Iroquois homeobox 3 antibody
    • Iroquois homeobox protein 3 antibody
    • Iroquois-class homeodomain protein irx-3 antibody
    • IRX 1 antibody
    • irx3 antibody
    • IRX3_HUMAN antibody
    • IRXB1 antibody
    see all

Images

  • All lanes : Anti-Iroquois homeobox protein 3/IRX3 antibody (ab217954) at 1/200 dilution

    Lane 1 : mouse brain lysate
    Lane 2 : mouse heart lysate

    Secondary
    All lanes : Goat Anti-Rabbit IgG Antibody (H+L), HRP Conjugated at 1/3000 dilution

    Predicted band size: 52 kDa

References

ab217954 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab217954.
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