Overview

  • Product name

    Anti-IRX5 antibody [IRX5C10G5]
    See all IRX5 primary antibodies
  • Description

    Mouse monoclonal [IRX5C10G5] to IRX5
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant IRX5 (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab50774 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Detects a band of approximately 32 kDa (predicted molecular weight: 54 kDa).

Target

  • Function

    Establishes the cardiac repolarization gradient by its repressive actions on the KCND2 potassium-channel gene. Required for retinal cone bipolar cell differentiation. May regulate contrast adaptation in the retina and control specific aspects of visual function in circuits of the mammalian retina (By similarity). Could be involved in the regulation of both the cell cycle and apoptosis in prostate cancer cells.
  • Sequence similarities

    Belongs to the TALE/IRO homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • Homeodomain protein IRX-2A antibody
    • Homeodomain protein IRXB2 antibody
    • Iroquois homeobox protein 5 antibody
    • Iroquois-class homeodomain protein IRX-5 antibody
    • IRX2A antibody
    • Irx5 antibody
    • IRX5_HUMAN antibody
    • IRXB2 antibody
    see all

Images

References

ab50774 has not yet been referenced specifically in any publications.

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