Recombinant Anti-Islet 1 antibody [EP4182] (ab109517)

Rabbit recombinant monoclonal Islet 1 antibody [EP4182]. Validated in WB, IP, IHC, Flow Cyt, ICC/IF and tested in Mouse, Chicken, Human. Cited in 18 publication(s). Independently reviewed in 4 review(s).

Publishing research using ab109517? Please let us know so that we can cite the reference in this datasheet.

ab109517 has been referenced in 21 publications.

  • Lim GS  et al. Microhexagon gradient array directs spatial diversification of spinal motor neurons. Theranostics 9:311-323 (2019). PubMed: 30809276
  • Zhang Q  et al. Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN. Theranostics 9:986-1000 (2019). PubMed: 30867811
  • Hor JH  et al. Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy. Cell Death Dis 9:1100 (2018). PubMed: 30368521
  • Rodriguez-Muela N  et al. Blocking p62-dependent SMN degradation ameliorates spinal muscular atrophy disease phenotypes. J Clin Invest 128:3008-3023 (2018). PubMed: 29672276
  • Michalak SM  et al. Ocular Motor Nerve Development in the Presence and Absence of Extraocular Muscle. Invest Ophthalmol Vis Sci 58:2388-2396 (2017). IHC-Fr ; Mouse . PubMed: 28437527
  • Ediger BN  et al. LIM domain-binding 1 maintains the terminally differentiated state of pancreatic ß cells. J Clin Invest 127:215-229 (2017). PubMed: 27941246
  • van Vliet PP  et al. Tissue specific requirements for WNT11 in developing outflow tract and dorsal mesenchymal protrusion. Dev Biol 429:249-259 (2017). PubMed: 28669819
  • Briggs JA  et al. Mouse embryonic stem cells can differentiate via multiple paths to the same state. Elife 6:N/A (2017). PubMed: 28990928
  • Liu Y  et al. Regulated differentiation of WERI-Rb-1 cells into retinal neuron-like cells. Int J Mol Med 40:1172-1184 (2017). PubMed: 28848998
  • Quadrato G  et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature 545:48-53 (2017). PubMed: 28445462
  • Dauber KL  et al. Dissecting the Roles of Polycomb Repressive Complex 2 Subunits in the Control of Skin Development. J Invest Dermatol 136:1647-55 (2016). PubMed: 26994968
  • Shi Q  et al. ISL1, a novel regulator of CCNB1, CCNB2 and c-MYC genes, promotes gastric cancer cell proliferation and tumor growth. Oncotarget 7:36489-36500 (2016). PubMed: 27183908
  • Wang Y  et al. ISL1 and JMJD3 synergistically control cardiac differentiation of embryonic stem cells. Nucleic Acids Res 44:6741-55 (2016). IP ; Human . PubMed: 27105846
  • Perdigoto CN  et al. Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet 12:e1006151 (2016). Mouse . PubMed: 27414999
  • Ostrowski SM  et al. Ectopic Atoh1 expression drives Merkel cell production in embryonic, postnatal and adult mouse epidermis. Development 142:2533-44 (2015). PubMed: 26138479
  • Meganathan K  et al. Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells. Cell Death Dis 6:e1756 (2015). PubMed: 25950486
  • Yang Z  et al. ISL-1 promotes pancreatic islet cell proliferation by forming an ISL-1/Set7/9/PDX-1 complex. Cell Cycle 14:3820-9 (2015). ChIP . PubMed: 26176407
  • Nasif S  et al. Islet 1 specifies the identity of hypothalamic melanocortin neurons and is critical for normal food intake and adiposity in adulthood. Proc Natl Acad Sci U S A 112:E1861-70 (2015). IHC-Fr ; Mouse . PubMed: 25825735
  • Ng SY  et al. Genome-wide RNA-Seq of Human Motor Neurons Implicates Selective ER Stress Activation in Spinal Muscular Atrophy. Cell Stem Cell 17:569-84 (2015). PubMed: 26321202
  • Zhang Q  et al. ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex. Mol Cancer 13:181 (2014). WB ; Human . PubMed: 25070240
  • Perdigoto CN  et al. Embryonic maturation of epidermal Merkel cells is controlled by a redundant transcription factor network. Development 141:4690-6 (2014). PubMed: 25468937

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