Isoconazole nitrate, antibacterial and antifungal agent (ab143206)

Overview

  • Product name

    Isoconazole nitrate, antibacterial and antifungal agent
  • Description

    Broad-spectrum antibacterial, antifungal agent
  • Biological description

    Broad-spectrum antibacterial, antifungal agent. Active against Gram-positive bacteria.
  • Purity

    > 99%
  • CAS Number

    24168-96-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]imidazole nitrate
  • Molecular weight

    479.14
  • Molecular formula

    C18H14Cl4N2O.HNO3
  • PubChem identifier

    159968
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1=CC(=C(C(=C1)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)Cl.[N+](=O)(O)[O-]
  • Source

    Synthetic

References

This product has been referenced in:

  • Veraldi S Isoconazole nitrate: a unique broad-spectrum antimicrobial azole effective in the treatment of dermatomycoses, both as monotherapy and in combination with corticosteroids. Mycoses 56 Suppl 1:3-15 (2013). Read more (PubMed: 23574019) »
  • Czaika VA  et al. Reactive oxygen species and the bacteriostatic and bactericidal effects of isoconazole nitrate. Mycoses 56 Suppl 1:16-22 (2013). Read more (PubMed: 23574020) »
  • Oyeka CA & Gugnani HC Isoconazole nitrate versus clotrimazole in foot and nail infections due to Hendersonula toruloidea, Scytalidium hyalinum and dermatophytes. Mycoses 35:357-61 (0). Read more (PubMed: 1302811) »

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