Isoliquiritigenin, antioxidant and antiangiogenic agent (ab143178)

Overview

  • Product name

    Isoliquiritigenin, antioxidant and antiangiogenic agent
  • Description

    Antioxidant and antiangiogenic agent
  • Biological description

    Antioxidant and antiangiogenic agent. Reduces NO release from LPS-stimulated macrophages. Inhibits VEGF-induced proliferation. Inhibits neoangiogenesis. Suppresses VEGF/VEGFR-2 signaling. Shows cardioprotective, anti-ischemic effects in vivo. Orally active.
  • Purity

    > 99%
  • CAS Number

    961-29-5
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Wang J  et al. [Anti-inflammation of flavonoid compounds from Dalbergia odorifera T. Chen in lipopolysaccharide stimulated RAW264.7 macrophages]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29:681-4 (2013). Read more (PubMed: 23837974) »
  • Wang Z  et al. Dietary compound isoliquiritigenin inhibits breast cancer neoangiogenesis via VEGF/VEGFR-2 signaling pathway. PLoS One 8:e68566 (2013). Read more (PubMed: 23861918) »
  • Zhang X  et al. Natural antioxidant-isoliquiritigenin ameliorates contractile dysfunction of hypoxic cardiomyocytes via AMPK signaling pathway. Mediators Inflamm 2013:390890 (2013). Read more (PubMed: 24163504) »

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