Anti-ITGB6 antibody (ab169271)
Key features and details
- Mouse polyclonal to ITGB6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-ITGB6 antibody
See all ITGB6 primary antibodies -
Description
Mouse polyclonal to ITGB6 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Sheep, Cow, Pig -
Immunogen
Recombinant full length protein within Human ITGB6 aa 1-800. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
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Positive control
- ITGB6 transfected 293T cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab169271 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 86 kDa.
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Notes |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 86 kDa. |
Target
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Function
Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. -
Sequence similarities
Belongs to the integrin beta chain family.
Contains 1 VWFA domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 282644 Cow
- Entrez Gene: 3694 Human
- Entrez Gene: 16420 Mouse
- Entrez Gene: 100037276 Pig
- Entrez Gene: 311061 Rat
- Entrez Gene: 443209 Sheep
- Omim: 147558 Human
- SwissProt: Q8SQB8 Cow
see all -
Alternative names
- Integrin beta-6 antibody
- ITB6_HUMAN antibody
- ITGB6 antibody
Images
Datasheets and documents
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Datasheet download
References (1)
ab169271 has been referenced in 1 publication.
- Ruoss S et al. Costamere protein expression and tissue composition of rotator cuff muscle after tendon release in sheep. J Orthop Res 36:272-281 (2018). WB . PubMed: 28574610