Product nameAnti-ITIH2/SHAP antibody
See all ITIH2/SHAP primary antibodies
DescriptionRabbit polyclonal to ITIH2/SHAP
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment corresponding to Human ITIH2/SHAP aa 124-321.
- WB: Fetal brain lysate IHC-P: Fetal brain tissue
Protein previously labeled as ITIH2.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 98% PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab118257 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 106 kDa (predicted molecular weight: 106 kDa).|
|IHC-P||1/100 - 1/500.|
FunctionMay act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
Sequence similaritiesBelongs to the ITIH family.
Contains 1 VIT domain.
Contains 1 VWFA domain.
modificationsHeavy chains are linked to bikunin via chondroitin 4-sulfate esterified to the alpha-carboxyl of the C-terminal aspartate after propeptide cleavage.
Phosphorylation sites are present in the extracelllular medium.
- Information by UniProt
- AI747202 antibody
- H2P antibody
- IGHEP2 antibody
ab118257 has been referenced in 2 publications.
- Martin J et al. Tumor Necrosis Factor-stimulated Gene 6 (TSG-6)-mediated Interactions with the Inter-a-inhibitor Heavy Chain 5 Facilitate Tumor Growth Factor ß1 (TGFß1)-dependent Fibroblast to Myofibroblast Differentiation. J Biol Chem 291:13789-801 (2016). PubMed: 27143355
- He H et al. Immobilized heavy chain-hyaluronic acid polarizes lipopolysaccharide-activated macrophages toward M2 phenotype. J Biol Chem 288:25792-803 (2013). WB ; Human . PubMed: 23878196