Anti-ITLN1 antibody (ab232885)
Key features and details
- Rabbit polyclonal to ITLN1
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-ITLN1 antibody
See all ITLN1 primary antibodies -
Description
Rabbit polyclonal to ITLN1 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Recombinant fragment (His-tag) corresponding to Human ITLN1 aa 1-300. Expressed in E. coli. N-terminal tag.
Database link: Q8WWA0 -
Positive control
- IHC-P: Human stomach and rectum tissue. WB: Recombinant human ITLN1 protein. Mouse small intestine lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
Antigen-specific affinity chromatography followed by Protein A affinity chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab232885 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 5 - 20 µg/ml.
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WB |
Use a concentration of 0.5 - 2 µg/ml.
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Notes |
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IHC-P
Use a concentration of 5 - 20 µg/ml. |
WB
Use a concentration of 0.5 - 2 µg/ml. |
Target
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Function
Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism. -
Tissue specificity
Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus. -
Sequence similarities
Contains 1 fibrinogen C-terminal domain. -
Developmental stage
Found in fetal small intestine and thymus. -
Post-translational
modificationsN-glycosylated. -
Cellular localization
Cell membrane. Secreted. Enriched in lipid rafts. - Information by UniProt
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Database links
- Entrez Gene: 55600 Human
- Entrez Gene: 16429 Mouse
- Omim: 609873 Human
- SwissProt: Q8WWA0 Human
- SwissProt: O88310 Mouse
- Unigene: 50813 Human
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Alternative names
- Endothelial lectin HL 1 antibody
- Endothelial lectin HL-1 antibody
- FLJ20022 antibody
see all
Images
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Anti-ITLN1 antibody (ab232885) at 2 µg/ml + Mouse small intestine lysate
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Formalin-fixed, paraffin-embedded human rectum tissue stained for ITLN1 with ab232885 at 20 µg/ml in immunohistochemical analysis. DAB staining.
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Formalin-fixed, paraffin-embedded human stomach tissue stained for ITLN1 with ab232885 at 20 µg/ml in immunohistochemical analysis. DAB staining.
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Anti-ITLN1 antibody (ab232885) at 2 µg/ml + Recombinant human ITLN1 protein
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab232885 has not yet been referenced specifically in any publications.