Anti-ITPKA antibody - C-terminal (ab175876)

Overview

  • Product name
    Anti-ITPKA antibody - C-terminal
    See all ITPKA primary antibodies
  • Description
    Rabbit polyclonal to ITPKA - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human ITPKA aa 353-382 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P23677

  • Positive control
    • K562 cell lysate; mouse lung lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Purification notes
    ab175876 is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab175876 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 51 kDa.

Target

  • Relevance
    ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of ITPKA is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.
  • Cellular localization
    cytosol
  • Database links
  • Alternative names
    • 1D myo inositol trisphosphate 3 kinase A antibody
    • EC 2.7.1.127 antibody
    • Inositol 1 4 5 trisphosphate 3 kinase A antibody
    • Inositol trisphosphate 3 kinase A antibody
    • IP3 3 kinase A antibody
    • IP3K A antibody
    • IP3KA antibody
    see all

Images

  • All lanes : Anti-ITPKA antibody - C-terminal (ab175876) at 1/1000 dilution

    Lane 1 : K562 cell lysate
    Lane 2 : Mouse lung lysate

    Lysates/proteins at 35 µg per lane.

    Predicted band size: 51 kDa

References

ab175876 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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