• Product name

    Anti-Jagged 2/JAG2 antibody [EPR3646]
    See all Jagged 2/JAG2 primary antibodies
  • Description

    Rabbit monoclonal [EPR3646] to Jagged 2/JAG2
  • Host species

  • Tested applications

    Suitable for: ICC/IF, WBmore details
    Unsuitable for: Flow Cyt,ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide within Human Jagged 2/JAG2 aa 50-150 (extracellular). The exact sequence is proprietary.

  • Positive control

    • HeLa, HUVEC and HT-29 cell lysates
  • General notes



     This product was previously labelled as Jagged 2


    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab109627 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration. PubMed: 24901044
WB 1/1000 - 1/10000. Predicted molecular weight: 133 kDa.
  • Application notes
    Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • Target

    • Relevance

      Jagged 2 is a Notch ligand involved in the mediation of Notch signaling. Jagged 2 is expressed in heart, placenta and skeletal muscle and to a lesser extend in pancreas. Very low expression in brain, lung, liver and kidney. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged 2 is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for Jagged 2.
    • Cellular localization

      Cell Membrane
    • Database links

    • Alternative names

      • D12Ggc2e antibody
      • HJ 2 antibody
      • HJ2 antibody
      • JAG 2 antibody
      • JAG2 antibody
      • Jagged 2 precursor antibody
      • Jagged2 antibody
      • Protein jagged 2 antibody
      • SER2 antibody
      • Syndactylism antibody
      see all


    • All lanes : Anti-Jagged 2/JAG2 antibody [EPR3646] (ab109627) at 1/1000 dilution

      Lane 1 : HeLa cell lysate
      Lane 2 : HUVEC cell lysate
      Lane 3 : HT-29 cell lysate

      Lysates/proteins at 10 µg per lane.

      All lanes : HRP labelled Goat anti-Rabbit at 1/2000 dilution

      Predicted band size: 133 kDa


    This product has been referenced in:

    • Huang F & Ma W The mechanism of blood concentrations of the Shenqi pill repairing injured epithelial cells of renal tubular in vitro. Exp Ther Med 14:246-250 (2017). Read more (PubMed: 28672921) »
    • Zhou J  et al. Protective role of microRNA-29a in denatured dermis and skin fibroblast cells after thermal injury. Biol Open N/A:N/A (2016). WB ; Human . Read more (PubMed: 26794609) »
    See all 3 Publications for this product

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