Overview

  • Product name

  • Description

    Rabbit polyclonal to JAKMIP1
  • Host species

    Rabbit
  • Specificity

    ab211296 is not predicted to cross-react with JAKMIP2.
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human JAKMIP1 (internal sequence). Raised against a 16 amino acid peptide near the center of Human JAKMIP1.
    Database link: Q96N16

  • Positive control

    • Rat brain whole cell lysate. Human brain (cortex) tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab211296 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
WB Use a concentration of 1 - 2 µg/ml.

Target

  • Function

    Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
  • Tissue specificity

    Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
  • Sequence similarities

    Belongs to the JAKMIP family.
  • Cellular localization

    Cytoplasm > cytoskeleton. Membrane. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ31564 antibody
    • GABA B receptor binding protein antibody
    • GABA-B receptor-binding protein antibody
    • GABABRBP antibody
    • Jak and microtubule interacting protein 1 antibody
    • JAKMIP 1 antibody
    • JAKMIP1 antibody
    • JAMIP1 antibody
    • Janus kinase and microtubule interacting protein 1 antibody
    • Janus kinase and microtubule-interacting protein 1 antibody
    • JKIP1_HUMAN antibody
    • Marlin 1 antibody
    • Marlin-1 antibody
    • MARLIN1 antibody
    • Multiple alpha-helices and RNA-linker protein 1 antibody
    • Multiple coiled coil GABABR1 binding protein antibody
    • OTTHUMP00000155144 antibody
    • OTTHUMP00000203209 antibody
    • OTTHUMP00000203210 antibody
    • OTTHUMP00000203212 antibody
    • OTTHUMP00000217225 antibody
    • OTTHUMP00000217781 antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed paraffin-embedded human brain (cortex) tissue labeling JAKMIP1 with ab211296 at 10 μg/mL.

  • Lane 1 : Anti-JAKMIP1 antibody (ab211296) at 1 µg/ml
    Lane 2 : Anti-JAKMIP1 antibody (ab211296) at 2 µg/ml

    All lanes : Rat brain whole cell lysate

References

ab211296 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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