Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Constituents: 2.68% PBS, 91% dH2O, 0.2% Monobasic dihydrogen potassium phosphate, 0.6% Dibasic monohydrogen sodium phosphate, 0.2% Potassium chloride, Whole serum, 8% Sodium chloride
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab67843 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 44 kDa).|
FunctionMay function in transmigration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells.
Tissue specificityExpression is restricted to the hematopoietic tissues with the exception of liver. Expressed in fetal liver, spleen and thymus.
Sequence similaritiesBelongs to the immunoglobulin superfamily.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.
DomainThe Ig-like V-type domain 2 mediates interaction with CXADR.
Cellular localizationCell junction. Cell membrane. Localized at the plasma membrane in areas of cell-cell contacts and at the cell surface of PMN.
- Information by UniProt
- adhesion molecule AMICA antibody
- Adhesion molecule interacting with CXADR antigen 1 antibody
- adhesion molecule interacts with CXADR antigen 1 antibody
All lanes : Anti-JAML antibody (ab67843) at 1/500 dilution
Lane 1 : JAML transfected 293T cell lysate
Lane 2 : Non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate secondary
antibody at 1/2500 dilution
Developed using the ECL technique.
Predicted band size: 44 kDa
Observed band size: 44 kDa
ab67843 has not yet been referenced specifically in any publications.