Recombinant Anti-JNK1 + JNK2 + JNK3 (phospho T183+T183+T221) antibody [EPR5693] (ab124956)

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ab124956 has been referenced in 55 publications.

  • Zhang X  et al. Tanshinone IIA induces apoptosis of ovarian cancer cells in vitro and in vivo through attenuation of PI3K/AKT/JNK signaling pathways. Oncol Lett 17:1896-1902 (2019). PubMed: 30675253
  • Wang M  et al. miR-302a inhibits human HepG2 and SMMC-7721 cells proliferation and promotes apoptosis by targeting MAP3K2 and PBX3. Sci Rep 9:2032 (2019). PubMed: 30765768
  • Gärtner K  et al. Engineering extracellular vesicles as novel treatment options: exploiting herpesviral immunity in CLL. J Extracell Vesicles 8:1573051 (2019). PubMed: 30788083
  • Wang C  et al. Quercetin ameliorates lipopolysaccharide-caused inflammatory damage via down-regulation of miR-221 in WI-38 cells. Exp Mol Pathol 108:1-8 (2019). PubMed: 30849307
  • Zhang W  et al. MicroRNA-451 inhibits vascular smooth muscle cell migration and intimal hyperplasia after vascular injury via Ywhaz/p38 MAPK pathway. Exp Cell Res 379:214-224 (2019). PubMed: 30930138
  • Liu L  et al. Astragalin Promotes Osteoblastic Differentiation in MC3T3-E1 Cells and Bone Formation in vivo. Front Endocrinol (Lausanne) 10:228 (2019). PubMed: 31040823
  • Liu X  et al. Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. J Exp Clin Cancer Res 38:184 (2019). PubMed: 31053160
  • Zheng XM  et al. MicroRNA-30e inhibits adhesion, migration, invasion and cell cycle progression of prostate cancer cells via inhibition of the activation of the MAPK signaling pathway by downregulating CHRM3. Int J Oncol 54:443-454 (2019). PubMed: 30483762
  • Feng SQ  et al. VEGF Antagonism Attenuates Cerebral Ischemia/Reperfusion-Induced Injury via Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis. Biol Pharm Bull 42:692-702 (2019). PubMed: 30828041
  • Sun G  et al. Flemingia philippinensis Flavonoids Relieve Bone Erosion and Inflammatory Mediators in CIA Mice by Downregulating NF-?B and MAPK Pathways. Mediators Inflamm 2019:5790291 (2019). PubMed: 30906224
  • Song B  et al. LncRNA ENST00000539653 acts as an oncogenic factor via MAPK signalling in papillary thyroid cancer. BMC Cancer 19:297 (2019). PubMed: 30940124
  • Yu M  et al. Lutein and Zeaxanthin Isomers Protect against Light-Induced Retinopathy via Decreasing Oxidative and Endoplasmic Reticulum Stress in BALB/cJ Mice. Nutrients 10:N/A (2018). PubMed: 29958415
  • Zheng Q  et al. Hyperosmotic Stress-Induced TRPM2 Channel Activation Stimulates NLRP3 Inflammasome Activity in Primary Human Corneal Epithelial Cells. Invest Ophthalmol Vis Sci 59:3259-3268 (2018). PubMed: 29971445
  • Luan L  et al. HOXD10 silencing suppresses human fibroblast-like synoviocyte migration in rheumatoid arthritis via downregulation of the p38/JNK pathway. Exp Ther Med 16:1621-1628 (2018). PubMed: 30186380
  • Jiang X Silencing of heart and neural crest derivatives expressed transcript 2 attenuates transforming growth factor-ß1-enhanced apoptosis of human bronchial epithelial cells. Oncol Lett 16:4997-5005 (2018). PubMed: 30250565
  • Yu L  et al. LncRNA-PCAT1 targeting miR-145-5p promotes TLR4-associated osteogenic differentiation of adipose-derived stem cells. J Cell Mol Med 22:6134-6147 (2018). PubMed: 30338912
  • Li S & He J Pilose antler polypeptide protects against sevoflurane-mediated neurocyte injury. Mol Med Rep 18:5353-5360 (2018). PubMed: 30365108
  • Li PC  et al. Seawater inhalation induces acute lung injury via ROS generation and the endoplasmic reticulum stress pathway. Int J Mol Med 41:2505-2516 (2018). PubMed: 29436612
  • Wang L  et al. TIPE-2 suppresses growth and aggressiveness of hepatocellular carcinoma cells through downregulation of the phosphoinositide 3-kinase/AKT signaling pathway. Mol Med Rep 17:7017-7026 (2018). PubMed: 29568863
  • Tang Q  et al. miR-223/Hsp70/JNK/JUN/miR-223 feedback loop modulates the chemoresistance of osteosarcoma to cisplatin. Biochem Biophys Res Commun 497:827-834 (2018). WB . PubMed: 29432736
  • Du J  et al. Andrographolide protects mouse astrocytes against hypoxia injury by promoting autophagy and S100B expression. Braz J Med Biol Res 51:e7061 (2018). PubMed: 29694508
  • Jin X  et al. Advanced Glycation End Products Enhance Murine Monocyte Proliferation in Bone Marrow and Prime Them into an Inflammatory Phenotype through MAPK Signaling. J Diabetes Res 2018:2527406 (2018). PubMed: 29765986
  • Zhang L  et al. Particle-induced SIRT1 downregulation promotes osteoclastogenesis and osteolysis through ER stress regulation. Biomed Pharmacother 104:300-306 (2018). WB ; Mouse . PubMed: 29775898
  • Zhang L  et al. MicroRNA-30b promotes lipopolysaccharide-induced inflammatory injury and alleviates autophagy through JNK and NF-?B pathways in HK-2 cells. Biomed Pharmacother 101:842-851 (2018). WB . PubMed: 29635893
  • Fang L  et al. MicroRNA-625-3p promotes the proliferation, migration and invasion of thyroid cancer cells by up-regulating astrocyte elevated gene 1. Biomed Pharmacother 102:203-211 (2018). WB ; Human . PubMed: 29558717
  • Bai D  et al. The effect of down-regulation of CCL5 on lipopolysaccharide-induced WI-38 fibroblast injury: a potential role for infantile pneumonia. Iran J Basic Med Sci 21:449-454 (2018). PubMed: 29922423
  • Liu X & Meng J Tanshinone IIA ameliorates lipopolysaccharide-induced inflammatory response in bronchial epithelium cell line BEAS-2B by down-regulating miR-27a. Biomed Pharmacother 104:158-164 (2018). PubMed: 29772436
  • Geng Q  et al. Physcion 8-O-ß-glucopyranoside extracted from Polygonum cuspidatum exhibits anti-proliferative and anti-inflammatory effects on MH7A rheumatoid arthritis-derived fibroblast-like synoviocytes through the TGF-ß/MAPK pathway. Int J Mol Med 42:745-754 (2018). PubMed: 29717774
  • Wang C  et al. Morin protects glucocorticoid-induced osteoporosis through regulating the mitogen-activated protein kinase signaling pathway. J Nat Med 72:929-936 (2018). PubMed: 30043216
  • Shi C  et al. Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways. Redox Biol 14:59-71 (2018). PubMed: 28869833
  • Liang X  et al. miR-326 functions as a tumor suppressor in human prostatic carcinoma by targeting Mucin1. Biomed Pharmacother 108:574-583 (2018). PubMed: 30243091
  • Ding M  et al. Schisandrin B protects human keratinocyte-derived HaCaT cells from tert-butyl hydroperoxide-induced oxidative damage through activating the Nrf2 signaling pathway. Int J Mol Med 42:3571-3581 (2018). PubMed: 30272282
  • Gao GY  et al. Ophiopogonin B induces the autophagy and apoptosis of colon cancer cells by activating JNK/c-Jun signaling pathway. Biomed Pharmacother 108:1208-1215 (2018). PubMed: 30372822
  • Liang N & Kitts DD Chlorogenic Acid (CGA) Isomers Alleviate Interleukin 8 (IL-8) Production in Caco-2 Cells by Decreasing Phosphorylation of p38 and Increasing Cell Integrity. Int J Mol Sci 19:N/A (2018). PubMed: 30518116
  • Xu D  et al. MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. PLoS Biol 16:e2006613 (2018). PubMed: 30566428
  • Wang Y  et al. Extracellular matrix deposited by Wharton's jelly mesenchymal stem cells enhances cell expansion and tissue specific lineage potential. Am J Transl Res 10:3465-3480 (2018). PubMed: 30662600
  • Li F  et al. Psoralen stimulates osteoblast proliferation through the activation of nuclear factor-?B-mitogen-activated protein kinase signaling. Exp Ther Med 14:2385-2391 (2017). PubMed: 28962172
  • Shao P  et al. MicroRNA-205-5p regulates the chemotherapeutic resistance of hepatocellular carcinoma cells by targeting PTEN/JNK/ANXA3 pathway. Am J Transl Res 9:4300-4307 (2017). PubMed: 28979703
  • Li J  et al. Investigation of highly expressed PCSK9 in atherosclerotic plaques and ox-LDL-induced endothelial cell apoptosis. Mol Med Rep 16:1817-1825 (2017). PubMed: 28656218
  • Wang H  et al. PDK2 promotes chondrogenic differentiation of mesenchymal stem cells by upregulation of Sox6 and activation of JNK/MAPK/ERK pathway. Braz J Med Biol Res 50:e5988 (2017). WB ; Rat . PubMed: 28225870
  • Wang B  et al. IL-34 Upregulated Th17 Production through Increased IL-6 Expression by Rheumatoid Fibroblast-Like Synoviocytes. Mediators Inflamm 2017:1567120 (2017). WB ; Human . PubMed: 28659662
  • Xiao Y  et al. TGF-ß/MAPK signaling mediates the effects of bone marrow mesenchymal stem cells on urinary control and interstitial cystitis after urinary bladder transplantation. Am J Transl Res 9:1193-1202 (2017). PubMed: 28386345
  • Wang Y  et al. Stromal cell-derived factor-1a and transforming growth factor-ß1 synergistically facilitate migration and chondrogenesis of synovium-derived stem cells through MAPK pathways. Am J Transl Res 9:2656-2667 (2017). PubMed: 28560013
  • Ren Y  et al. Hyperosmolarity-induced AQP5 upregulation promotes inflammation and cell death via JNK1/2 Activation in human corneal epithelial cells. Sci Rep 7:4727 (2017). WB . PubMed: 28680052
  • Li H  et al. YAP Inhibits the Apoptosis and Migration of Human Rectal Cancer Cells via Suppression of JNK-Drp1-Mitochondrial Fission-HtrA2/Omi Pathways. Cell Physiol Biochem 44:2073-2089 (2017). PubMed: 29241219
  • Zhang F  et al. A Novel c-Jun N-terminal Kinase (JNK) Signaling Complex Involved in Neuronal Migration during Brain Development. J Biol Chem 291:11466-75 (2016). PubMed: 27026702
  • Shen W  et al. TIFA suppresses hepatocellular carcinoma progression via MALT1-dependent and -independent signaling pathways. Signal Transduct Target Ther 1:16013 (2016). PubMed: 29263897
  • Yu Y  et al. Regulatory T cells exhibit neuroprotective effect in a mouse model of traumatic brain injury. Mol Med Rep 14:5556-5566 (2016). WB . PubMed: 27878274
  • Kang K  et al. Carnosic acid slows photoreceptor degeneration in the Pde6b(rd10) mouse model of retinitis pigmentosa. Sci Rep 6:22632 (2016). IHC, WB . PubMed: 26961159
  • Li C  et al. LFG-500, a newly synthesized flavonoid, attenuates lipopolysaccharide-induced acute lung injury and inflammation in mice. Biochem Pharmacol 113:57-69 (2016). PubMed: 27206337
  • Jiang C  et al. Rescue therapy with Tanshinone IIA hinders transition of acute kidney injury to chronic kidney disease via targeting GSK3ß. Sci Rep 6:36698 (2016). WB ; Mouse . PubMed: 27857162
  • Li C  et al. Inhibitory effects of kaempferol on the invasion of human breast carcinoma cells by downregulating the expression and activity of matrix metalloproteinase-9. Biochem Cell Biol 93:16-27 (2015). Human . PubMed: 25453494
  • Li C  et al. Inhibitory Effects of Isorhamnetin on the Invasion of Human Breast Carcinoma Cells by Downregulating the Expression and Activity of Matrix Metalloproteinase-2/9. Nutr Cancer 67:1191-200 (2015). Human . PubMed: 26359917
  • Liu X  et al. Mechanical Tension Promotes the Osteogenic Differentiation of Rat Tendon-derived Stem Cells Through the Wnt5a/Wnt5b/JNK Signaling Pathway. Cell Physiol Biochem 36:517-30 (2015). PubMed: 25966835
  • Yan T  et al. Luteolin inhibits behavioral sensitization by blocking methamphetamine-induced MAPK pathway activation in the caudate putamen in mice. PLoS One 9:e98981 (2014). WB ; Mouse . PubMed: 24901319

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