Anti-Junctional Adhesion Molecule 1/JAM-A antibody (ab89203)

Overview

  • Product name

    Anti-Junctional Adhesion Molecule 1/JAM-A antibody
    See all Junctional Adhesion Molecule 1/JAM-A primary antibodies
  • Description

    Mouse polyclonal to Junctional Adhesion Molecule 1/JAM-A
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Full length protein corresponding to Human Junctional Adhesion Molecule 1/JAM-A.

  • Positive control

    • Human spleen lysate, Junctional Adhesion Molecule 1/JAM-A transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab89203 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 33 kDa.

Target

  • Function

    Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
  • Sequence similarities

    Belongs to the immunoglobulin superfamily.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Post-translational
    modifications

    N-glycosylated.
  • Cellular localization

    Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD 321 antibody
    • CD321 antibody
    • CD321 antigen antibody
    • ESTM33 antibody
    • F11 receptor antibody
    • F11R antibody
    • JAM 1 antibody
    • JAM A antibody
    • JAM antibody
    • JAM-1 antibody
    • JAM-A antibody
    • JAM1 antibody
    • JAM1_HUMAN antibody
    • JAMA antibody
    • JCAM antibody
    • Jcam1 antibody
    • Junction adhesion molecule 1 antibody
    • Junction adhesion molecule, mouse, homolog of antibody
    • Junctional adhesion molecule 1 antibody
    • Junctional adhesion molecule A antibody
    • KAT antibody
    • Ly106 antibody
    • PAM 1 antibody
    • PAM-1 antibody
    • PAM1 antibody
    • Platelet adhesion molecule 1 antibody
    • Platelet adhesion molecule antibody
    • Platelet F11 receptor antibody
    • PRO301 antibody
    • UNQ264 antibody
    see all

Images

  • Anti-Junctional Adhesion Molecule 1/JAM-A antibody (ab89203) at 1/500 dilution + Human spleen lysate at 50 µg

    Predicted band size: 33 kDa
    Observed band size: 35 kDa
    why is the actual band size different from the predicted?

  • All lanes : Anti-Junctional Adhesion Molecule 1/JAM-A antibody (ab89203) at 1/500 dilution

    Lane 1 : Junctional Adhesion Molecule 1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Predicted band size: 33 kDa
    Observed band size: 37 kDa why is the actual band size different from the predicted?

References

ab89203 has not yet been referenced specifically in any publications.

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