Key features and details
- Rabbit monoclonal [RM275] to Junctional Adhesion Molecule 1/JAM-A - N-terminal
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Junctional Adhesion Molecule 1/JAM-A antibody [RM275] - N-terminal
See all Junctional Adhesion Molecule 1/JAM-A primary antibodies
DescriptionRabbit monoclonal [RM275] to Junctional Adhesion Molecule 1/JAM-A - N-terminal
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human Junctional Adhesion Molecule 1/JAM-A (N terminal).
Database link: Q9Y624
- WB: HEK-293 cell lysate. IHC-P: Human kidney tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
Concentration information loading...
PurityProtein A purified
Purification notesPurified from an animal origin–free culture supernatant.
Our Abpromise guarantee covers the use of ab238313 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/250 - 1/1000. Predicted molecular weight: 32 kDa.|
|IHC-P||1/2000 - 1/10000.|
FunctionSeems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Sequence similaritiesBelongs to the immunoglobulin superfamily.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.
Cellular localizationCell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
- Information by UniProt
- CD 321 antibody
- CD321 antibody
- CD321 antigen antibody
Anti-Junctional Adhesion Molecule 1/JAM-A antibody [RM275] - N-terminal (ab238313) at 1/250 dilution + HEK-293 (Human epithelial cell line from embryonic kidney) cell lysate
Predicted band size: 32 kDa
Formalin-fixed, paraffin-embedded human kidney tissue stained for Junctional Adhesion Molecule 1/JAM-A using ab238313 at 1/10,0000 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab238313 has not yet been referenced specifically in any publications.