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Signal Transduction Protein Trafficking ER Proteins
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Anti-JWA antibody (ab113631)

  • Datasheet
  • SDS
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Western blot - Anti-JWA antibody (ab113631)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-JWA antibody (ab113631)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-JWA antibody (ab113631)

Key features and details

  • Goat polyclonal to JWA
  • Suitable for: WB, IHC-P
  • Reacts with: Human
  • Isotype: IgG

You may also be interested in

Secondary
Product image
Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
Protein
Product image
Recombinant Human JWA protein (ab161039)

View more associated products

Overview

  • Product name

    Anti-JWA antibody
    See all JWA primary antibodies
  • Description

    Goat polyclonal to JWA
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Cynomolgus monkey, Orangutan
  • Immunogen

    Synthetic peptide:

    C-NRLTDYISKVKE

    , corresponding to C terminal amino acids 177-188 of Human JWA
    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive control

    • Human small intestine (submucosal plexus) and tonsil tissues; Human brain tissue lysate
  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    pH: 7.30
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 99% Tris buffered saline
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Protein Trafficking
    • ER Proteins
    • Cell Biology
    • Cell Cycle
    • Cell differentiation

Associated products

  • Compatible Secondaries

    • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
    • Donkey Anti-Goat IgG H&L (HRP) (ab205723)
  • Isotype control

    • Goat IgG, polyclonal - Isotype Control (ab37373)
  • Recombinant Protein

    • Recombinant Human JWA protein (ab161039)

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab113631 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 21 kDa.
IHC-P
Use a concentration of 3.75 µg/ml.
Notes
WB
Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 21 kDa.
IHC-P
Use a concentration of 3.75 µg/ml.

Target

  • Function

    Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic.
  • Sequence similarities

    Belongs to the PRA1 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Cytoplasm. Also exists as a soluble form in the cytoplasm. Associated with microtubules.
  • Target information above from: UniProt accession O75915 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 10550 Human
    • Omim: 605709 Human
    • SwissProt: Q4R4R4 Cynomolgus monkey
    • SwissProt: O75915 Human
    • SwissProt: Q5R4X8 Orangutan
    • Unigene: 518060 Human
    • Unigene: 745255 Human
    • Alternative names

      • Addicsin antibody
      • ADP ribosylation factor like protein 6 interacting protein 5 antibody
      • ADP ribosylation like factor 6 interacting protein 5 antibody
      • ADP-ribosylation factor-like protein 6-interacting protein 5 antibody
      • Aip 5 antibody
      • Aip-5 antibody
      • Aip5 antibody
      • ARL 6 interacting protein 5 antibody
      • ARL-6-interacting protein 5 antibody
      • ARL6IP5 antibody
      • Cytoskeleton related vitamin A responsive protein antibody
      • Cytoskeleton-related vitamin A-responsive protein antibody
      • Dermal papilla derived protein 11 antibody
      • Dermal papilla-derived protein 11 antibody
      • DERP 11 antibody
      • DERP11 antibody
      • Glutamate transporter EAAC1-interacting protein antibody
      • Glutamate transporter EEAC 1 associated protein antibody
      • Glutamate transporter EEAC1 associated protein antibody
      • GTRAP3 18 antibody
      • GTRAP3-18 antibody
      • Hp 22 antibody
      • Hp22 antibody
      • HSPC 127 antibody
      • HSPC127 antibody
      • JM 5 antibody
      • JM5 antibody
      • JMX antibody
      • JWA antibody
      • PRA 1 domain family 3 antibody
      • PRA 2 antibody
      • PRA1 domain family 3 antibody
      • PRA1 family protein 3 antibody
      • PRA2 antibody
      • PRAF 3 antibody
      • PRAF3 antibody
      • PRAF3_HUMAN antibody
      • Prenylated Rab acceptor protein 2 antibody
      • Protein JWa antibody
      • Putative MAPK activating protein PM27 antibody
      • Putative MAPK-activating protein PM27 antibody
      see all

    Images

    • Western blot - Anti-JWA antibody (ab113631)
      Western blot - Anti-JWA antibody (ab113631)
      Anti-JWA antibody (ab113631) at 0.1 µg/ml + Human brain tissue lysate (in RIPA buffer) at 35 µg

      Developed using the ECL technique.

      Predicted band size: 21 kDa



      Primary incubation: 1 hour.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-JWA antibody (ab113631)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-JWA antibody (ab113631)
      ab113631, at 3.75 µg/ml, staining JWA in formalin fixed, paraffin embedded Human small intestine tissue (submucosal plexus) tissue by Immunohistochemistry.
    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-JWA antibody (ab113631)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-JWA antibody (ab113631)
      ab113631, at 3.75 µg/ml, staining JWA in formalin fixed, paraffin embedded Human small tonsil tissue by Immunohistochemistry.

    Protocols

    • Western blot protocols
    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab113631? Please let us know so that we can cite the reference in this datasheet.

    ab113631 has not yet been referenced specifically in any publications.

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