Overview

  • Product name

    Anti-K Cadherin/CDH6 antibody
    See all K Cadherin/CDH6 primary antibodies
  • Description

    Rabbit polyclonal to K Cadherin/CDH6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Fusion protein corresponding to Human K Cadherin/CDH6 (internal sequence). (BC000019)
    Database link: P55285-2

  • Positive control

    • HeLa, A549 and HT29 cell lysates; Human liver cancer tissue lysate. Human brain tissue.
  • General notes

     This product was previously labelled as K Cadherin

     

Properties

Applications

Our Abpromise guarantee covers the use of ab197845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 74 kDa.
IHC-P 1/50 - 1/200.

Target

  • Function

    Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • Tissue specificity

    Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
  • Sequence similarities

    Contains 5 cadherin domains.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CAD6 antibody
    • CADH6_HUMAN antibody
    • Cadherin 6 antibody
    • Cadherin 6 type 2 antibody
    • Cadherin 6 type 2 K cadherin (fetal kidney) antibody
    • Cadherin fetal kidney antibody
    • Cadherin-6 antibody
    • Cadherin6 antibody
    • CDH 6 antibody
    • Cdh6 antibody
    • K-cadherin antibody
    • KCAD antibody
    • Kidney cadherin antibody
    see all

Images

  • All lanes : Anti-K Cadherin/CDH6 antibody (ab197845) at 1/500 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : A549 cell lysate
    Lane 3 : Human liver cancer tissue lysate
    Lane 4 : HT29 cell lysate

    Lysates/proteins at 40 µg per lane.

    Predicted band size: 74 kDa


    Exposure time: 2 minutes


    Gel: 8%SDS-PAGE

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling K Cadherin/CDH6 with ab197845 at 1/50 dilution.

References

This product has been referenced in:

  • Karthikeyan S  et al. Cadherin-6 type 2, K-cadherin (CDH6) is regulated by mutant p53 in the fallopian tube but is not expressed in the ovarian surface. Oncotarget 7:69871-69882 (2016). WB, IHC . Read more (PubMed: 27563818) »
See 1 Publication for this product

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