Recombinant Anti-K73 antibody [EPR12564-39] (ab181383)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR12564-39] to K73
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
Overview
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Product name
Anti-K73 antibody [EPR12564-39]
See all K73 primary antibodies -
Description
Rabbit monoclonal [EPR12564-39] to K73 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Recombinant fragment within Human K73. The exact sequence is proprietary.
Database link: Q86Y46 -
Positive control
- Human skin, rat skin and mouse skin lysate
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR12564-39 -
Isotype
IgG
Associated products
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Alternative Versions
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab181383 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/10000 - 1/50000. Predicted molecular weight: 59 kDa.
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Notes |
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WB
1/10000 - 1/50000. Predicted molecular weight: 59 kDa. |
Target
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Function
Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. -
Tissue specificity
Highly expressed in hair follicles from scalp. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, it is expressed between the lowermost bulb region of the cuticle and the region where Henle cells undergo abrupt terminal differentiation. Detected up to the uppermost cortex region where cuticle cells terminally differentiate (at protein level). -
Sequence similarities
Belongs to the intermediate filament family. - Information by UniProt
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Database links
- Entrez Gene: 319101 Human
- Entrez Gene: 223915 Mouse
- Entrez Gene: 300248 Rat
- Omim: 608247 Human
- SwissProt: Q86Y46 Human
- SwissProt: Q6NXH9 Mouse
- SwissProt: Q6IG03 Rat
- Unigene: 55410 Human
see all -
Alternative names
- CK-73 antibody
- Cytokeratin-73 antibody
- IRT6IRS3 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
Certificate of Compliance
References (1)
ab181383 has been referenced in 1 publication.
- Xie S et al. Self-assembled complete hair follicle organoids by coculture of neonatal mouse epidermal cells and dermal cells in Matrigel. Ann Transl Med 10:767 (2022). PubMed: 35965801