Key features and details
- Rabbit polyclonal to KAL1
- Suitable for: ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-KAL1 antibody
DescriptionRabbit polyclonal to KAL1
Tested applicationsSuitable for: ELISA, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide of Human KAL1, conjugated to KLH.
- Human skeletal muscle tissue
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.09% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab115270 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||1/1 - 1/1000.|
|IHC-P||Use a concentration of 20 - 40 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionMay be an adhesion-like molecule with anti-protease activity.
Involvement in diseaseDefects in KAL1 are the cause of Kallmann syndrome type 1 (KAL1) [MIM:308700]; also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In some patients other developmental anomalies can be present, which include renal agenesis, cleft lip and/or palate, selective tooth agenesis, and bimanual synkinesis. In some cases anosmia may be absent or inconspicuous.
Sequence similaritiesContains 4 fibronectin type-III domains.
Contains 1 WAP domain.
Cellular localizationCell surface.
- Information by UniProt
- Adhesion molecule-like X-linked antibody
- ADMLX antibody
- Anosmin-1 antibody
ab115270, at 40 µg/ml, staining KAL1 in formalin fixed, paraffin embedded Human skeletal muscle tissue by Immunohistochemistry. After incubation with the primary antibody, slides were incubated with biotinylated goat anti-rabbit IgG secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
ab115270 has not yet been referenced specifically in any publications.