Key features and details
- Rabbit polyclonal to Kallikrein 14
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Kallikrein 14 antibody
See all Kallikrein 14 primary antibodies
DescriptionRabbit polyclonal to Kallikrein 14
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human Kallikrein 14 conjugated to Keyhole Limpet Haemocyanin (KLH).
Database link: Q9P0G3
- Rat brain tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 0.01% BSA, 50% Glycerol
Aqueous buffered solution
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab203226 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.
When using a fluorescent probe the recommended dilution is 1/50 – 1/200
|WB||1/100 - 1/1000. Predicted molecular weight: 29 kDa.|
FunctionSerine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.
Tissue specificityHighly expressed in CNS, bone marrow and fetal liver. Also expressed in breast, thyroid, kidney, colon, pancreas, spleen, prostate, uterus, small intestine, placenta and skeletal muscle. Among 40 tissues tested, the highest expression is detected in skin followed by breast and prostate (at protein level). Expressed in stratum corneum by sweat ducts and sweat glands and detected in sweat (at protein level).
Sequence similaritiesBelongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.
modificationsProteolytic cleavage of the activation peptide produces the active enzyme.
Cellular localizationSecreted > extracellular space.
- Information by UniProt
- hK14 antibody
- Kallikrein 14 antibody
- Kallikrein like protein 6 antibody
Immunohistochemical analysis of formalin-fixed and paraffin-embedded rat brain labeling Kallikrein 14 with ab203226 at 1/200 dilution with DAB staining.
Immunohistochemical analysis of formalin-fixed and paraffin-embedded rat brain labeling Kallikrein 14 with ab203226 at 1/200 dilution overnight at 4°C. The secondary antibody was Goat Anti-Rabbit IgG, Cy3 conjugated used at 1/200 dilution for 40 minutes at 37°C.
ab203226 has not yet been referenced specifically in any publications.