• Product name

    Anti-Kallikrein 14 antibody [EPR7209]
    See all Kallikrein 14 primary antibodies
  • Description

    Rabbit monoclonal [EPR7209] to Kallikrein 14
  • Host species

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Kallikrein 14 aa 250-350 (C terminal). The exact sequence is proprietary.

  • Positive control

    • SH-SY5Y, fetal liver, fetal kidney, HACAT and prostate cancer lysates
  • General notes



    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab128957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 29, 31 kDa (predicted molecular weight: 29 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis.
    • Tissue specificity

      Highly expressed in CNS, bone marrow and fetal liver. Also expressed in breast, thyroid, kidney, colon, pancreas, spleen, prostate, uterus, small intestine, placenta and skeletal muscle. Among 40 tissues tested, the highest expression is detected in skin followed by breast and prostate (at protein level). Expressed in stratum corneum by sweat ducts and sweat glands and detected in sweat (at protein level).
    • Sequence similarities

      Belongs to the peptidase S1 family. Kallikrein subfamily.
      Contains 1 peptidase S1 domain.
    • Post-translational

      Proteolytic cleavage of the activation peptide produces the active enzyme.
    • Cellular localization

      Secreted > extracellular space.
    • Information by UniProt
    • Database links

    • Alternative names

      • hK14 antibody
      • Kallikrein 14 antibody
      • Kallikrein like protein 6 antibody
      • Kallikrein-14 antibody
      • Kallikrein-like protein 6 antibody
      • KLK L6 antibody
      • KLK-L6 antibody
      • KLK14 antibody
      • KLK14_HUMAN antibody
      see all


    • All lanes : Anti-Kallikrein 14 antibody [EPR7209] (ab128957) at 1/1000 dilution

      Lane 1 : SH-SY5Y cell lysate
      Lane 2 : Fetal liver lysate
      Lane 3 : Fetal kidney lysate
      Lane 4 : HACAT cell lysate
      Lane 5 : Prostate cancer lysate

      Lysates/proteins at 10 µg per lane.

      Predicted band size: 29 kDa
      Observed band size: 29,31 kDa
      why is the actual band size different from the predicted?

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD


    This product has been referenced in:

    • Williams MR  et al. Staphylococcus aureus Induces Increased Serine Protease Activity in Keratinocytes. J Invest Dermatol 137:377-384 (2017). Read more (PubMed: 27765722) »
    See 1 Publication for this product

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