Overview

  • Product name

    Anti-Kallikrein 4 antibody
    See all Kallikrein 4 primary antibodies
  • Description

    Rabbit Polyclonal to Kallikrein 4
  • Host species

    Rabbit
  • Specificity

    ab197657 detects endogenous level of total Kallikrein 4 protein.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Fusion protein within Human Kallikrein 4 (internal sequence). The exact sequence is proprietary. Fusion protein corresponding to a region derived from internal residues of human Kallikrein 4. NCBI Accession No. BC069429. The protein fusion partner is GST.
    Database link: Q9Y5K2

  • Positive control

    • Human cervical cancer and thyroid cancer tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab197657 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/15 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Tissue specificity

    Expressed in prostate.
  • Involvement in disease

    Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:204700]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.
  • Sequence similarities

    Belongs to the peptidase S1 family. Kallikrein subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • 7S nerve growth factor alpha chain antibody
    • AI2A1 antibody
    • Alpha-NGF antibody
    • Androgen-regulated message 1 antibody
    • ARM1 antibody
    • EC 3.4.21.- antibody
    • EMSP 1 antibody
    • EMSP antibody
    • EMSP1 antibody
    • Enamel Matrix Serine Protease 1 antibody
    • Enamel matrix serine proteinase 1 antibody
    • HK4 antibody
    • Kallikrein 1-related peptidase-like b4 antibody
    • Kallikrein 4 (prostase, enamel matrix, prostate) antibody
    • Kallikrein 4 antibody
    • Kallikrein antibody
    • Kallikrein L1 antibody
    • Kallikrein like protein 1 antibody
    • Kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) antibody
    • Kallikrein-4 antibody
    • Kallikrein-like protein 1 antibody
    • Kallikrein-related peptidase 4 antibody
    • KLK 4 antibody
    • KLK L1 antibody
    • KLK-L1 antibody
    • KLK4 antibody
    • KLK4_HUMAN antibody
    • MGC116827 antibody
    • MGC116828 antibody
    • Prostase antibody
    • Protease Serine 17 antibody
    • PRSS 17 antibody
    • PRSS17 antibody
    • PSTS antibody
    • Serine protease 17 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling Kallikrein 4 using ab197657 at a 1/15 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling Kallikrein 4 using ab197657 at a 1/15 dilution.

References

ab197657 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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