Anti-Kallikrein 4 antibody (ab197657)
Key features and details
- Rabbit polyclonal to Kallikrein 4
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Kallikrein 4 antibody
See all Kallikrein 4 primary antibodies -
Description
Rabbit polyclonal to Kallikrein 4 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse -
Immunogen
Fusion protein within Human Kallikrein 4 (internal sequence). The exact sequence is proprietary. Fusion protein corresponding to a region derived from internal residues of human Kallikrein 4. NCBI Accession No. BC069429. The protein fusion partner is GST.
Database link: Q9Y5K2 -
Positive control
- Human cervical cancer and thyroid cancer tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab197657 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/15 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/15 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Tissue specificity
Expressed in prostate. -
Involvement in disease
Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:204700]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel. -
Sequence similarities
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 9622 Human
- Entrez Gene: 56640 Mouse
- Omim: 603767 Human
- SwissProt: Q9Y5K2 Human
- SwissProt: P00757 Mouse
- Unigene: 218366 Human
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Alternative names
- 7S nerve growth factor alpha chain antibody
- AI2A1 antibody
- Alpha-NGF antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab197657 has been referenced in 1 publication.
- Gao J et al. Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein-related peptidase 4 and tight junction proteins in ameloblasts. Int J Mol Med 46:179-190 (2020). PubMed: 32626909