Key features and details
- Rabbit polyclonal to Kallikrein 5
- Isotype: IgG
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Product nameAnti-Kallikrein 5 antibody
See all Kallikrein 5 primary antibodies
DescriptionRabbit polyclonal to Kallikrein 5
Synthetic peptide, corresponding to amino acids 280-293 of Human KLK5.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.4
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
FunctionMay be involved in desquamation.
Tissue specificityExpressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin.
Sequence similaritiesBelongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.
- Information by UniProt
- HK5 antibody
- Kallikrein 5 antibody
- Kallikrein L2 antibody
ab7283 has been referenced in 4 publications.
- Furio L et al. Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome. J Exp Med 211:499-513 (2014). PubMed: 24534191
- Bonnart C et al. Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing. J Clin Invest 120:871-82 (2010). IHC-P ; Human . PubMed: 20179351
- Yanagi T et al. Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12-deficient harlequin ichthyosis model mice. Am J Pathol 177:106-18 (2010). WB, IHC-P ; Mouse . PubMed: 20489143
- Di WL et al. A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins. Br J Dermatol 161:404-12 (2009). WB ; Human . PubMed: 19438860
Customer reviews and Q&As
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