Anti-Kallikrein 5 antibody (ab7283)
Key features and details
- Rabbit polyclonal to Kallikrein 5
- Isotype: IgG
Overview
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Product name
Anti-Kallikrein 5 antibody
See all Kallikrein 5 primary antibodies -
Description
Rabbit polyclonal to Kallikrein 5 -
Host species
Rabbit -
Immunogen
Synthetic peptide, corresponding to amino acids 280-293 of Human KLK5.
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General notes
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Target
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Function
May be involved in desquamation. -
Tissue specificity
Expressed in skin, breast, brain and testis. Expressed at the stratum granulosum of palmar skin. -
Sequence similarities
Belongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain. -
Cellular localization
Secreted. - Information by UniProt
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Alternative names
- HK5 antibody
- Kallikrein 5 antibody
- Kallikrein L2 antibody
see all
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab7283 has been referenced in 4 publications.
- Furio L et al. Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome. J Exp Med 211:499-513 (2014). PubMed: 24534191
- Bonnart C et al. Elastase 2 is expressed in human and mouse epidermis and impairs skin barrier function in Netherton syndrome through filaggrin and lipid misprocessing. J Clin Invest 120:871-82 (2010). IHC-P ; Human . PubMed: 20179351
- Yanagi T et al. Self-improvement of keratinocyte differentiation defects during skin maturation in ABCA12-deficient harlequin ichthyosis model mice. Am J Pathol 177:106-18 (2010). WB, IHC-P ; Mouse . PubMed: 20489143
- Di WL et al. A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins. Br J Dermatol 161:404-12 (2009). WB ; Human . PubMed: 19438860