Key features and details
- Rabbit polyclonal to Kallikrein 7/KLK7
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Kallikrein 7/KLK7 antibody
See all Kallikrein 7/KLK7 primary antibodies
DescriptionRabbit polyclonal to Kallikrein 7/KLK7
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human Kallikrein 7/KLK7 aa 36-130.
Database link: P49862
- 293T, A431, H1299, HeLa, HepG2, MOLT4 and Raji cell lysates.
This product was previously labelled as Kallikrein 7
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
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Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab154707 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 28 kDa.|
FunctionMay catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. SCCE cleaves insulin B chain at '6-Leu-
-Tyr-26' and '26-Tyr-
-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.
Tissue specificityAbundantly expressed in the skin and is expressed by keratinocytes in the epidermis. Also expressed in the brain, mammary gland, cerebellum, spinal cord and kidney. Lower levels in salivary glands, uterus, thymus, thyroid, placenta, trachea and testis. Up-regulated in ovarian carcinoma, especially late-stage serous carcinoma, compared with normal ovaries and benign adenomas (at protein level).
Sequence similaritiesBelongs to the peptidase S1 family. Kallikrein subfamily.
Contains 1 peptidase S1 domain.
Cellular localizationSecreted. In ovarian carcinoma, secreted and also observed at the apical membrane and in cytoplasm at the invasive front.
- Information by UniProt
- Chymotryptic stratum corneum antibody
- hK 7 antibody
- hK7 antibody
ab154707 has not yet been referenced specifically in any publications.