Key features and details
- Rabbit polyclonal to KAT2A / GCN5
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-KAT2A / GCN5 antibody
See all KAT2A / GCN5 primary antibodies
DescriptionRabbit polyclonal to KAT2A / GCN5
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Rat, Chicken
Synthetic peptide, corresponding to a region within C terminal amino acids 775-837 of Human KAT2A/ GCN5 (UniProt ID: Q92830).
- A431, H1299 and HeLa whole cell lysates.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab137515 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 94 kDa.|
FunctionFunctions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Tissue specificityExpressed in all tissues tested, with most abundant expression in ovary.
Sequence similaritiesBelongs to the GCN5 family.
Contains 1 bromo domain.
Contains 1 N-acetyltransferase domain.
- Information by UniProt
- 1110051E14Rik antibody
- AW212720 antibody
- EC 126.96.36.199 antibody
ab137515 has been referenced in 1 publication.
- Stilling RM et al. K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation. EMBO J 33:1912-27 (2014). Mouse . PubMed: 25024434