Key features and details
- Mouse monoclonal [AT3G13] to KAT2A / GCN5
- Suitable for: WB, ICC/IF
- Isotype: IgG2a
Product nameAnti-KAT2A / GCN5 antibody [AT3G13]
See all KAT2A / GCN5 primary antibodies
DescriptionMouse monoclonal [AT3G13] to KAT2A / GCN5
Tested applicationsSuitable for: WB, ICC/IFmore details
Recombinant fragment corresponding to Human KAT2A/ GCN5 aa 411-837.
MGGGSNSSLS LDSAGAEPMP GEKRTLPENL TLEDAKRLRV MGDIPMELVN EVMLTITDPA AMLGPETSLL SANAARDETA RLEERRGIIE FHVIGNSLTP KANRRVLLWL VGLQNVFSHQ LPRMPKEYIA RLVFDPKHKT LALIKDGRVI GGICFRMFPT QGFTEIVFCA VTSNEQVKGY GTHLMNHLKE YHIKHNILYF LTYADEYAIG YFKKQGFSKD IKVPKSRYLG YIKDYEGATL MECELNPRIP YTELSHIIKK QKEIIKKLIE RKQAQIRKVY PGLSCFKEGV RQIPVESVPG IRETGWKPLG KEKGKELKDP DQLYTTLKNL LAQIKSHPSA WPFMEPVKKS EAPDYYEVIR FPIDLKTMTE RLRSRYYVTR KLFVADLQRV IANCREYNPP DSEYCRCASA LEKFFYFKLK EGGLIDK
Database link: Q92830
- HeLa cells and HeLa whole cell lysate (ab150035).
Derived from hybridization of mouse F0 myeloma cells.
This product was changed from ascites to tissue culture supernatant on 28/02/19. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 89% PBS, 10% Glycerol
Concentration information loading...
PurityProtein G purified
Light chain typekappa
Our Abpromise guarantee covers the use of ab208097 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/250 - 1/1000. Predicted molecular weight: 94 kDa.|
|ICC/IF||1/250 - 1/500.|
FunctionFunctions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Tissue specificityExpressed in all tissues tested, with most abundant expression in ovary.
Sequence similaritiesBelongs to the GCN5 family.
Contains 1 bromo domain.
Contains 1 N-acetyltransferase domain.
- Information by UniProt
- 1110051E14Rik antibody
- AW212720 antibody
- EC 188.8.131.52 antibody
ab208097 has been referenced in 2 publications.
- Liao W et al. Upregulation of GPNCA is associated with poor prognosis through enhancement of tumor growth via regulating GSK3B. Sci Rep 10:2044 (2020). PubMed: 32029792
- Cramer T et al. Early-life epigenetic changes along the corticotropin-releasing hormone (CRH) gene influence resilience or vulnerability to heat stress later in life. Mol Psychiatry 24:1013-1026 (2019). PubMed: 30742007