Key features and details
- Rabbit polyclonal to KAT6B / MORF
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-KAT6B / MORF antibody
See all KAT6B / MORF primary antibodies
DescriptionRabbit polyclonal to KAT6B / MORF
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide within Human KAT6B/ MORF. The exact sequence is proprietary.
Database link: Q8WYB5
- HEK293T, Raw264.7 and NIH 3T3 whole cell lysates.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.05% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab191994 was affinity-purified from Rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Our Abpromise guarantee covers the use of ab191994 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500. Predicted molecular weight: 231 kDa.|
FunctionHistone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
Tissue specificityUbiquitously expressed, with high levels in heart, pancreas, testis and ovary.
Involvement in diseaseNote=A chromosomal aberration involving MYST4 may be a cause acute myeloid leukemias. Translocation t(10;16)(q22;p13) with CREBBP.
Sequence similaritiesBelongs to the MYST (SAS/MOZ) family.
Contains 1 C2HC-type zinc finger.
Contains 1 H15 (linker histone H1/H5 globular) domain.
Contains 2 PHD-type zinc fingers.
DomainThe N-terminus is involved in transcriptional activation while the C-terminus is involved in transcriptional repression.
- Information by UniProt
- DKFZp313G1618 antibody
- FLJ90335 antibody
- Histone acetyltransferase MORF antibody
ab191994 has been referenced in 1 publication.
- Wu Y et al. High methylation of lysine acetyltransferase 6B is associated with the Cobb angle in patients with congenital scoliosis. J Transl Med 18:210 (2020). PubMed: 32448279