Overview

  • Product name

  • Description

    Rabbit polyclonal to KCHIP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Cow, Pig
  • Immunogen

    Recombinant fragment within Human KCHIP1 (internal sequence). The exact sequence is proprietary.
    Database link: Q9NZI2

  • Positive control

    • WB: NT2/D1 whole cell lysate; mouse brain whole cell lysate. IHC-P: SW480 xenograft.
  • General notes

     This product was previously labelled as KCNIP1

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab229013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/1000.
WB 1/500 - 1/3000. Predicted molecular weight: 26 kDa.

Target

  • Function

    Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.
  • Tissue specificity

    Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus.
  • Sequence similarities

    Belongs to the recoverin family.
    Contains 4 EF-hand domains.
  • Cellular localization

    Cell membrane. Cytoplasm. Cell projection, dendrite.
  • Information by UniProt
  • Database links

  • Form

    There are 3 isoforms produced by alternative splicing.
  • Alternative names

    • A type potassium channel modulatory protein 1 antibody
    • A-type potassium channel modulatory protein 1 antibody
    • KChIP1 antibody
    • KCIP1_HUMAN antibody
    • Kcnip1 antibody
    • Kv channel interacting protein 1 antibody
    • Kv channel-interacting protein 1 antibody
    • MGC9 antibody
    • MGC95 antibody
    • Potassium channel interacting protein 1 antibody
    • Potassium channel-interacting protein 1 antibody
    • VABP antibody
    • Vesicle APC binding protein antibody
    • Vesicle APC-binding protein antibody
    see all

Images

  • Anti-KCHIP1 antibody (ab229013) at 1/1000 dilution + NT2/D1 (human embryonal carcinoma cell line) whole cell lysate at 30 µg

    Developed using the ECL technique.

    Predicted band size: 26 kDa



    12% SDS-PAGE

  • Anti-KCHIP1 antibody (ab229013) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg

    Developed using the ECL technique.

    Predicted band size: 26 kDa



    12% SDS-PAGE

  • Paraffin-embedded SW480 xenograft stained for KCHIP1 with ab229013 at 1/100 dilution in immunohistochemical analysis.

References

ab229013 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229013.
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