Recombinant Anti-KCHIP1 antibody [EPR7624] - BSA and Azide free (ab248639)
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Overview
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Product name
Anti-KCHIP1 antibody [EPR7624] - BSA and Azide free
See all KCHIP1 primary antibodies -
Description
Rabbit monoclonal [EPR7624] to KCHIP1 - BSA and Azide free -
Host species
Rabbit -
Tested applications
Suitable for: WB, Flow Cyt, IPmore details
Unsuitable for: ICC or IHC-P -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide within Human KCHIP1 aa 50-150. The exact sequence is proprietary.
Database link: Q9NZI2 -
General notes
ab248639 is the carrier-free version of ab133753 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.
Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Ab248639 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.
Maxpar® is a trademark of Fluidigm Canada Inc.
This product was previously labelled as KCNIP1
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Dissociation constant (KD)
KD = 5.00 x 10 -12 M Learn more about KD -
Storage buffer
Constituent: PBS -
Carrier free
Yes -
Concentration information loading... -
Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
EPR7624 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Conjugation kits
Applications
Our Abpromise guarantee covers the use of ab248639 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use at an assay dependent concentration. Detects a band of approximately 30 kDa (predicted molecular weight: 26 kDa). | |
| Flow Cyt | Use at an assay dependent concentration. | |
| IP | Use at an assay dependent concentration. |
Target
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Function
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface. -
Tissue specificity
Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus. -
Sequence similarities
Belongs to the recoverin family.
Contains 4 EF-hand domains. -
Cellular localization
Cell membrane. Cytoplasm. Cell projection, dendrite. - Information by UniProt
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Database links
- Entrez Gene: 30820 Human
- Entrez Gene: 70357 Mouse
- Entrez Gene: 65023 Rat
- Omim: 604660 Human
- SwissProt: Q9NZI2 Human
- SwissProt: Q9JJ57 Mouse
- SwissProt: Q8R426 Rat
- Unigene: 484111 Human
see all -
Form
There are 3 isoforms produced by alternative splicing. -
Alternative names
- A type potassium channel modulatory protein 1 antibody
- A-type potassium channel modulatory protein 1 antibody
- KChIP1 antibody
see all
Datasheets and documents
References
ab248639 has not yet been referenced specifically in any publications.
