Overview

  • Product name

  • Description

    Rabbit polyclonal to KCNA3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human KCNA3 aa 505-540 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    CQHLSS SAEELRKARS NSTLSKSEYM VIEEGGMNHS


    Database link: P22001

  • Positive control

    • HepG2 lysate.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 1% BSA, 50% Glycerol
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab216696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 63 kDa.

Target

  • Function

    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • Sequence similarities

    Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
  • Domain

    The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • HGK 5 antibody
    • HGK5 antibody
    • HLK 3 antibody
    • HLK3 antibody
    • HPCN 3 antibody
    • HPCN3 antibody
    • HuKIII antibody
    • KCNA 3 antibody
    • Kcna3 antibody
    • KCNA3_HUMAN antibody
    • KV1.3 antibody
    • MK 3 antibody
    • MK3 antibody
    • OTTHUMP00000032397 antibody
    • PCN 3 antibody
    • PCN3 antibody
    • Potassium channel 3 antibody
    • Potassium voltage gated channel shaker related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily A member 3 antibody
    • Potassium voltage-gated channel subfamily A member 3 antibody
    • Type n potassium channel antibody
    • Voltage gated potassium channel protein Kv1.3 antibody
    • Voltage gated potassium channel subunit Kv1.3 antibody
    • Voltage-gated K(+) channel HuKIII antibody
    • Voltage-gated potassium channel subunit Kv1.3 antibody
    see all

Images

  • Anti-KCNA3 antibody (ab216696) at 1/300 dilution + HepG2 lysate

    Secondary
    Goat Anti-Rabbit IgG Antibody (H+L), HRP at 1/5000 dilution

    Predicted band size: 63 kDa

References

ab216696 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab216696.
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