Overview

  • Product name

    Anti-KCNG4 antibody
  • Description

    Rabbit polyclonal to KCNG4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 57-519 of Human KCNG4 (Uniprot ID: Q8TDN1).

  • Positive control

    • PC3 whole cell lysate; Human BT483 xenograft tissue; Mouse testis tissue.
  • General notes

    Keep as concentrated solution.

Properties

Applications

Our Abpromise guarantee covers the use of ab155772 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 59 kDa.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
  • Tissue specificity

    Highly expressed in brain, and at lower levels in liver, small intestine and colon.
  • Sequence similarities

    Belongs to the potassium channel family. G (TC 1.A.1.2) subfamily. Kv6.4/KCNG4 sub-subfamily.
  • Domain

    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization

    Cell membrane. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.
  • Information by UniProt
  • Database links

  • Alternative names

    • Kcng4 antibody
    • KCNG4_HUMAN antibody
    • KV6.3 antibody
    • KV6.4 antibody
    • MGC129609 antibody
    • MGC4558 antibody
    • Potassium voltage-gated channel subfamily G member 4 antibody
    • Voltage gated potassium channel Kv6.3 antibody
    • Voltage-gated potassium channel subunit Kv6.4 antibody
    see all

Images

  • Anti-KCNG4 antibody (ab155772) at 1/1000 dilution + PC3 whole cell lysate at 30 µg

    Predicted band size: 59 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin-embedded Mouse testis tissue labeling KCNG4 with ab155772 at 1/500 dilution.
  • Immunohistochemical analysis of paraffin-embedded Human BT483 xenograft tissue labeling KCNG4 with ab155772 at 1/500 dilution.

References

ab155772 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Sample
Mouse Tissue sections (Cerebellum + Brain stem)
Antigen retrieval step
Heat mediated - Buffer/Enzyme Used: 10mM Natrium-Citrate
Permeabilization
Yes - 0.4% Triton
Specification
Cerebellum + Brain stem
Blocking step
Normal Horse Serum as blocking agent for 1 hour(s) and 30 minute(s) · Concentration: 10% · Temperature: RT°C
Fixative
Paraformaldehyde

François Blot

Verified customer

Submitted Oct 27 2016

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up