Product nameAnti-KCNK3/TASK1 antibody [N374/48] - C-terminal (FITC)
See all KCNK3/TASK1 primary antibodies
DescriptionMouse monoclonal [N374/48] to KCNK3/TASK1 - C-terminal (FITC)
ConjugationFITC. Ex: 493nm, Em: 528nm
Specificityab186344 does not cross-react with KCNK9.
Tested applicationsSuitable for: WB, Flow Cyt, ICC/IF, ELISA, IHC-Fr, ICC, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat
Recombinant fragment corresponding to Rat KCNK3/TASK1 aa 251-411 (C terminal).
AEDEKRDAEHRALLTHNGQAGGLGGLSCLSGSLGDGVRPRDPVTCAAAAG GMGVGVGVGGSGFRNVYAEMLHFQSMCSCLWYKSREKLQYSIPMIIPRDL STSDTCVEHSHSSPGGGGRYSDTPSHPCLCSGTQRSAISSVSTGLHSLAT FRGLMKRRSSV
Database link: O54912
- Rat brain lysate.
The clone number has been updated from S374-48 to N374/48, both clone numbers name the same antibody clone.
This product was previously labelled as KCNK3
Storage instructionsShipped at 4°C. Store at +4°C. Store In the Dark.
Storage bufferpH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab186344 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 50 kDa (predicted molecular weight: 45 kDa).|
|Flow Cyt||Use at an assay dependent concentration.
ab91368 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.
|ICC/IF||Use at an assay dependent concentration.|
|ELISA||Use at an assay dependent concentration.|
|IHC-Fr||Use at an assay dependent concentration.|
|ICC||Use at an assay dependent concentration.|
|IHC-P||Use at an assay dependent concentration.|
FunctionpH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.
Tissue specificityWidespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.
Involvement in diseasePulmonary hypertension, primary, 4
Sequence similaritiesBelongs to the two pore domain potassium channel (TC 1.A.1.8) family.
- Information by UniProt
- Acid sensitive potassium channel protein TASK 1 antibody
- Acid sensitive potassium channel protein TASK antibody
- Acid-sensitive potassium channel protein TASK-1 antibody
ab186344 has not yet been referenced specifically in any publications.