Overview

  • Product name

    Anti-KCNK6 antibody
  • Description

    Rabbit polyclonal to KCNK6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human KCNK6 aa 253-308.
    Sequence:

    LQTFRHVSDLHGLTELILLPPPCPASFNADEDDRVDILGPQPESHQQLSA SSHTDY


    Database link: Q9Y257

  • Positive control

    • IHC-P: Human placenta tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab224656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Exhibits outward rectification in a physiological K(+) gradient and mild inward rectification in symmetrical K(+) conditions.
  • Tissue specificity

    Widespread expression, detected in all tissues tested except for skeletal muscle. Strongest expression in placenta, pancreas, heart, colon and spleen, lower levels detected in peripheral blood leukocytes, lung, liver, kidney and thymus. Lowest expression detected in brain.
  • Sequence similarities

    Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • D7Ertd764e antibody
    • FLJ12282 antibody
    • Inward rectifying potassium channel protein TWIK 2 antibody
    • Inward rectifying potassium channel protein TWIK-2 antibody
    • K2p6.1 antibody
    • K2P6.1 potassium channel antibody
    • KCNK6 antibody
    • KCNK6_HUMAN antibody
    • KCNK8 antibody
    • Potassium channel subfamily K member 6 antibody
    • Potassium channel, subfamily K, member 6 (TWIK 2) antibody
    • Potassium channel, subfamily K, member 6 antibody
    • TOSS antibody
    • TWIK 2 antibody
    • TWIK 2 two pore domain K+ channel antibody
    • TWIK originated sodium similarity sequence antibody
    • TWIK-originated similarity sequence antibody
    • TWIK2 antibody
    see all

Images

  • Paraffin-embedded human placenta tissue stained for KCNK6 using ab224656 at 1/200 dilution in immunohistochemical analysis.

References

ab224656 has not yet been referenced specifically in any publications.

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