Product nameKCNN2/SK2 peptide
Our Abpromise guarantee covers the use of ab186680 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-KCNN2/SK2 antibody (ab99457)
Protein previously known as KCNN2.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C.
ReconstitutionDissolve the peptide in distilled water and then top it up with the appropriate buffer.
- Apamin sensitive small conductance Ca2+ activated potassium
- Apamin sensitive small conductance Ca2+ activated potassium channel
FunctionForms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Tissue specificityWidely expressed.
Sequence similaritiesBelongs to the potassium channel KCNN family. KCa2.2/KCNN2 subfamily.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab186680 has not yet been referenced specifically in any publications.