Anti-KCNN3/SK3 antibody (ab220864)
Key features and details
- Rabbit polyclonal to KCNN3/SK3
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-KCNN3/SK3 antibody
See all KCNN3/SK3 primary antibodies -
Description
Rabbit polyclonal to KCNN3/SK3 -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Pig
-
Immunogen
Recombinant fragment corresponding to Human KCNN3/SK3 aa 202-267.
Sequence:NLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQHA GTTASSTTFPKANKRK
Database link: Q9UGI6 -
Positive control
- PC-3 cells.
-
General notes
Protein previously labeled as KCNN3.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab220864 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ICC/IF | Use a concentration of 0.25 - 2 µg/ml. Fixation/Permeabilization: PFA/Triton X-100. |
Target
-
Function
Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. -
Sequence similarities
Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 3782 Human
- Entrez Gene: 140493 Mouse
- Entrez Gene: 397045 Pig
- Entrez Gene: 54263 Rat
- Omim: 602983 Human
- SwissProt: Q9UGI6 Human
- SwissProt: P58391 Mouse
- SwissProt: P58392 Pig
see all -
Alternative names
- hSK3 antibody
- KCa2.3 antibody
- Kcnn3 antibody
see all
Images
-
Immunocytochemistry/ Immunofluorescence - Anti-KCNN3/SK3 antibody (ab220864)
Immunofluorescent analysis of PFA-fixed, Triton X-100 permeabilized PC-3 cells labeling KCNN3/SK3 with ab220864 at 4 μg/ml (green).
Protocols
Datasheets and documents
References (0)
ab220864 has not yet been referenced specifically in any publications.
