Anti-KCNN3/SK3 antibody (ab220864)

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Overview

  • Product name

    Anti-KCNN3/SK3 antibody
    See all KCNN3/SK3 primary antibodies

  • Description

    Rabbit polyclonal to KCNN3/SK3

  • Host species

    Rabbit

  • Tested applications

    Suitable for: ICC/IFmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig

  • Immunogen

    Recombinant fragment corresponding to Human KCNN3/SK3 aa 202-267.
    Sequence:

    NLIEAETEGQPLQLFSPSNPPEIVISSREDNHAHQTLLHHPNATHNHQHA GTTASSTTFPKANKRK


    Database link: Q9UGI6

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • Positive control

    • PC-3 cells.

  • General notes

    Protein previously labeled as KCNN3.

Properties

Applications

Our Abpromise guarantee covers the use of ab220864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100.

Target

  • Function

    Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.

  • Sequence similarities

    Belongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • hSK3 antibody
    • KCa2.3 antibody
    • Kcnn3 antibody
    • KCNN3_HUMAN antibody
    • Potassium calcium activated channel subfamily N member 3 antibody
    • Potassium channel calcium activated intermediate/small conductance subfamily N alpha member 3 antibody
    • Potassium channel, calcium activated, intermediate/small conductance, subfamily N, member 3 antibody
    • Potassium intermediate/small conductance calcium activated channel subfamily N member 3 antibody
    • SK3 antibody
    • SKCa 3 antibody
    • SKCa3 antibody
    • Small conductance calcium-activated potassium channel protein 3 antibody
    see all

Images

  • Immunocytochemistry/ Immunofluorescence - Anti-KCNN3/SK3 antibody (ab220864)
    Immunocytochemistry/ Immunofluorescence - Anti-KCNN3/SK3 antibody (ab220864)

    Immunofluorescent analysis of PFA-fixed, Triton X-100 permeabilized PC-3 cells labeling KCNN3/SK3 with ab220864 at 4 μg/ml (green).

References

ab220864 has not yet been referenced specifically in any publications.

Publishing research using ab220864? Please let us know so that we can cite the reference in this datasheet.

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