Product nameAnti-KCNN3/SK3 antibody
See all KCNN3/SK3 primary antibodies
DescriptionRabbit polyclonal to KCNN3/SK3
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Rat
- WB: HEK-293T cells. IHC-P: Human cerebral cortex tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab272577 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.04 - 0.4 µg/ml.|
|IHC-P||1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionForms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.
Sequence similaritiesBelongs to the potassium channel KCNN family. KCa2.3/KCNN3 subfamily.
- Information by UniProt
- hSK3 antibody
- KCa2.3 antibody
- Kcnn3 antibody
Lanes 2-3 : Anti-KCNN3/SK3 antibody (ab272577) at 0.4 µg/ml
Lane 1 : Molecular weight ladder
Lane 2 : Control (vector only transfected HEK-293T lysate)
Lane 3 : KCNN3 over-expression lysate (mammalian HEK-293T cells)
Paraffin-embedded formalin-fixed Human cerebral cortex tissue stained for KCNN3/SK3 using ab272577 at 1/1000 in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab272577 has not yet been referenced specifically in any publications.