Key features and details
- Rabbit polyclonal to KCNS3
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-KCNS3 antibody
DescriptionRabbit polyclonal to KCNS3
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat, Rabbit
Recombinant fragment corresponding to Human KCNS3 aa 1-180.
MVFGEFFHRPGQDEELVNLNVGGFKQSVDQSTLLRFPHTRLGKLLTCHSE EAILELCDDYSVADKEYYFDRNPSLFRYVLNFYYTGKLHVMEELCVFSFC QEIEYWGINELFIDSCCSNRYQERKEENHEKDWDQKSHDVSTDSSFEESS LFEKELEKFDTLRFGQLRKKIWIRMENPAY
Database link: Q9BQ31
- WB: Mouse lung tissue lysate. IHC-P: Human lung tissue and gastric cancer tissue.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab230343 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/20 - 1/200.|
|WB||1/1000 - 1/5000. Detects a band of approximately 56, 35 kDa (predicted molecular weight: 56 kDa).|
FunctionPotassium channel subunit. Modulates channel activity and reduces the ion flow.
Tissue specificityDetected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung.
Sequence similaritiesBelongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
DomainThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
Cellular localizationCell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.
- Information by UniProt
- Delayed rectifier K(+) channel alpha subunit 3 antibody
- Delayed rectifier K+ channel alpha subunit 3 antibody
- Delayed-rectifier K(+) channel alpha subunit 3 antibody
Anti-KCNS3 antibody (ab230343) at 1/1000 dilution + mouse lung tissue lysate
Goat polyclonal to rabbit IgG at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 56 kDa
Observed band size: 35,56 kDa why is the actual band size different from the predicted?
Paraffin-embedded human lung tissue stained for KCNS3 with ab230343 at a 1/100 dilution in immunohistochemical analysis.
Paraffin-embedded human gastric cancer tissue stained for KCNS3 with ab230343 at a 1/100 dilution in immunohistochemical analysis.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab230343 has not yet been referenced specifically in any publications.