Overview

  • Product name
  • Description
    Chicken polyclonal to KCNS3
  • Host species
    Chicken
  • Specificity
    ab26164 recognises potassium voltage-gated channel delayed-rectifier protein S3.
  • Tested applications
    Suitable for: WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to amino acids 26-224 of Human KCNS3

  • Positive control
    • 293 cell extract, Hela cell extract

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Constituent: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgY
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab26164 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).
ICC 1/200.

Target

  • Function
    Potassium channel subunit. Modulates channel activity and reduces the ion flow.
  • Tissue specificity
    Detected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung.
  • Sequence similarities
    Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
  • Domain
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • Cellular localization
    Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.
  • Information by UniProt
  • Database links
  • Alternative names
    • Delayed rectifier K(+) channel alpha subunit 3 antibody
    • Delayed rectifier K+ channel alpha subunit 3 antibody
    • Delayed-rectifier K(+) channel alpha subunit 3 antibody
    • KCNS 3 antibody
    • Kcns3 antibody
    • KCNS3_HUMAN antibody
    • KV 9.3 antibody
    • KV9.3 antibody
    • MGC9481 antibody
    • Potassium voltage gated channel delayed rectifier protein S3 antibody
    • Potassium voltage gated channel delayed rectifier subfamily S member 3 antibody
    • Potassium voltage gated channel subfamily S member 3 antibody
    • Potassium voltage-gated channel subfamily S member 3 antibody
    • Shab related delayed rectifier K+ channel alpha subunit 3 antibody
    • Voltage gated potassium channel subunit Kv9.3 antibody
    • Voltage-gated potassium channel subunit Kv9.3 antibody
    see all

Images

  • E coli-derived fusion protein (1), 293 cell extract (2), and Hela cell extract (3) as test antigen. Affinity-purified IgY dilution: 1:2000 (or 1:500 for cell extract), Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

References

This product has been referenced in:
  • Hristov KL  et al. Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle. Am J Physiol Cell Physiol 302:C1599-608 (2012). WB ; Human . Read more (PubMed: 22422395) »
  • Chen M  et al. Voltage-gated K(+) channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle. Am J Physiol Regul Integr Comp Physiol 299:R177-84 (2010). WB ; Rat . Read more (PubMed: 20393158) »
See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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