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Chicken polyclonal to KCNS3
ab26164 recognises potassium voltage-gated channel delayed-rectifier protein S3.
Mouse, Rat, Human
Synthetic peptide, corresponding to amino acids 26-224 of Human KCNS3
293 cell extract, Hela cell extract
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500. Detects a band of approximately 56 kDa (predicted molecular weight: 56 kDa).
Potassium channel subunit. Modulates channel activity and reduces the ion flow.
Detected in most tissues, but not in peripheral blood lymphocytes. The highest levels of expression are in lung.
Belongs to the potassium channel family. S (TC 1.A.1.2) subfamily. Kv9.3/KCNS3 sub-subfamily.
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
Cell membrane. May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1.
Information by UniProt
Delayed rectifier K(+) channel alpha subunit 3 antibody
Delayed rectifier K+ channel alpha subunit 3 antibody
Delayed-rectifier K(+) channel alpha subunit 3 antibody
Western blot - Anti-KCNS3 antibody (ab26164)
E coli-derived fusion protein (1), 293 cell extract (2), and Hela cell extract (3) as test antigen. Affinity-purified IgY dilution: 1:2000 (or 1:500 for cell extract), Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
This product has been referenced in:
et al. Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle. Am J Physiol Cell Physiol 302:C1599-608 (2012).
Read more (PubMed: 22422395) »
et al. Voltage-gated K(+) channels sensitive to stromatoxin-1 regulate myogenic and neurogenic contractions of rat urinary bladder smooth muscle. Am J Physiol Regul Integr Comp Physiol 299:R177-84 (2010).
Read more (PubMed: 20393158) »
See all 3 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"