Overview

  • Product name

    Anti-KDS antibody [EPR4947(2)]
    See all KDS primary antibodies
  • Description

    Rabbit monoclonal [EPR4947(2)] to KDS
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human KDS aa 850 to the C-terminus (C terminal). The exact sequence is proprietary.
    Database link: Q9H2K8

  • Positive control

    • Jurkat, 293T, K562 and HeLa cell lysates
  • General notes

    This antibody was developed as part of a collaboration between Epitomics and the lab of Melanie Cobb at UT Southwestern Medical Center.

     This product was previously labelled as TAOK3

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab150388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 105 kDa.
IHC-P Use at an assay dependent concentration.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Function

      Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF). When overexpressed, may activate ERK1/ERK2 and JNK/SAPK.
    • Tissue specificity

      Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
    • Sequence similarities

      Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
      Contains 1 protein kinase domain.
    • Post-translational
      modifications

      Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localization

      Cytoplasm. Cell membrane. Also localized to the peripheral cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • CTCL tumor antigen HD CL 09 antibody
      • CTCL-associated antigen HD-CL-09 antibody
      • Cutaneous T cell lymphoma tumor antigen HD CL 09 antibody
      • Cutaneous T-cell lymphoma-associated antigen HD-CL-09 antibody
      • Dendritic cell derived protein kinase antibody
      • Dendritic cell-derived protein kinase antibody
      • DKFZp666H245 antibody
      • DPK antibody
      • FLJ31808 antibody
      • hKFC A antibody
      • hKFC-A antibody
      • JIK antibody
      • JNK/SAPK inhibitory kinase antibody
      • JNK/SAPK-inhibitory kinase antibody
      • Jun kinase inhibitory kinase antibody
      • Jun kinase-inhibitory kinase antibody
      • KDS antibody
      • Kinase from chicken homolog A antibody
      • MAP3K18 antibody
      • Serine kinase antibody
      • Serine/threonine-protein kinase TAO3 antibody
      • STE20 like kinase antibody
      • TAO kinase 3 antibody
      • TAOK3 antibody
      • TAOK3_HUMAN antibody
      • Thousand and one amino acid protein 3 antibody
      see all

    Images

    • All lanes : Anti-KDS antibody [EPR4947(2)] (ab150388) at 1/1000 dilution

      Lane 1 : Jurkat cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : K562 cell lysate
      Lane 4 : HeLa cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit antibody at 1/2000 dilution

      Predicted band size: 105 kDa

    References

    ab150388 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab150388.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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