• Product name
  • Description
    Rabbit polyclonal to KIBRA
  • Host species
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 289-327 of Human KIBRA (NP_056053.1).

  • Positive control
    • ZR-75-1 cell line lysate. This antibody gave a positive result in IHC in the following FFPE tissue: Human Kidney.


  • Form
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab107637 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab107637 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/100 - 1/500. Predicted molecular weight: 125 kDa.


  • Relevance
    KIBRA is a WW domain containing protein, first identified by yeast 2-hybrid analysis of a human brain cDNA expression library. Gene expression studies have shown that KIBRA is expressed in memory-related brain structures including the hippocampus (dentate gyrus and the CA1 region) and the temporal lobe, 2 key regions for memory, and that the expression of specific KIBRA alleles is significantly associated with memory performance.
  • Cellular localization
    Cytoplasm. Cytoplasm › perinuclear region. Nucleus. Cell projection › ruffle membrane. Note: Co-localizes with PRKCZ in the perinuclear region.
  • Database links
  • Alternative names
    • FLJ10865 antibody
    • FLJ23369 antibody
    • HBeAg-binding protein 3 antibody
    • HBEBP3 antibody
    • HBEBP36 antibody
    • KIAA0869 antibody
    • KIBRA antibody
    • Kidney and brain protein antibody
    • Protein KIBRA antibody
    • Protein WWC1 antibody
    • WW and C2 domain containing 1 antibody
    • WW C2 and coiled-coil domain containing 1 antibody
    • WW domain-containing protein 1 antibody
    • WWC1 antibody
    see all


  • IHC image of KIBRA staining in Human Kidney formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab107637, 10 µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.


    For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

  • Anti-KIBRA antibody (ab107637) at 1/100 dilution + ZR-75-1 cell line lysate at 35 µg

    Predicted band size: 125 kDa


This product has been referenced in:
  • Mudduwa L  et al. KIBRA; a novel biomarker predicting recurrence free survival of breast cancer patients receiving adjuvant therapy. BMC Cancer 18:589 (2018). Read more (PubMed: 29793439) »
  • Deng L  et al. Luteolin, a novel p90 ribosomal S6 kinase inhibitor, suppresses proliferation and migration in leukemia cells. Oncol Lett 13:1370-1378 (2017). Read more (PubMed: 28454264) »

See all 3 Publications for this product

Customer reviews and Q&As

Thank you for contacting us.

This antibody has not been tested in IHC and does not have any publications for this application.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice...

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