Key features and details
- Rabbit polyclonal to KIBRA
- Suitable for: IHC-P, WB
- Reacts with: Rat, Human
- Isotype: IgG
Product nameAnti-KIBRA antibody
DescriptionRabbit polyclonal to KIBRA
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse
- Rat kidney and brain tissues.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 50% Glycerol, 1% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab216508 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/100 - 1/500.|
RelevanceKIBRA is a WW domain containing protein, first identified by yeast 2-hybrid analysis of a human brain cDNA expression library. Gene expression studies have shown that KIBRA is expressed in memory-related brain structures including the hippocampus (dentate gyrus and the CA1 region) and the temporal lobe, 2 key regions for memory, and that the expression of specific KIBRA alleles is significantly associated with memory performance.
Cellular localizationCytoplasm. Cytoplasm › perinuclear region. Nucleus. Cell projection › ruffle membrane. Note: Co-localizes with PRKCZ in the perinuclear region.
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All lanes : Anti-KIBRA antibody (ab216508) at 1/1000 dilution
Lane 1 : Siha cell lysates
Lane 2 : A431 cell lysates
Lane 3 : MCF-7 cell lysates
Lane 4 : U2OS cell lysates
All lanes : Conjugated secondary antibody at 1/20000 dilution
Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat kidney tissue labeling KIBRA with ab216508 1/200 dilution, followed by secondary antibody detection and DAB staining.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat brain tissue labeling KIBRA with ab216508 1/200 dilution, followed by secondary antibody detection and DAB staining.
ab216508 has not yet been referenced specifically in any publications.