Overview

  • Product name

    Anti-KIBRA antibody
  • Description

    Rabbit polyclonal to KIBRA
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide within Human KIBRA aa 370-420 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    LEMARKRLEKDLQAARDTQSKALTERLKLNSKRNQLVRELEEATRQVATL H


    Database link: Q8IX03

  • Positive control

    • Rat kidney and brain tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab216508 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.
WB 1/1000.

Target

  • Relevance

    KIBRA is a WW domain containing protein, first identified by yeast 2-hybrid analysis of a human brain cDNA expression library. Gene expression studies have shown that KIBRA is expressed in memory-related brain structures including the hippocampus (dentate gyrus and the CA1 region) and the temporal lobe, 2 key regions for memory, and that the expression of specific KIBRA alleles is significantly associated with memory performance.
  • Cellular localization

    Cytoplasm. Cytoplasm › perinuclear region. Nucleus. Cell projection › ruffle membrane. Note: Co-localizes with PRKCZ in the perinuclear region.
  • Database links

  • Alternative names

    • FLJ10865 antibody
    • FLJ23369 antibody
    • HBeAg-binding protein 3 antibody
    • HBEBP3 antibody
    • HBEBP36 antibody
    • KIAA0869 antibody
    • KIBRA antibody
    • Kidney and brain protein antibody
    • Protein KIBRA antibody
    • Protein WWC1 antibody
    • WW and C2 domain containing 1 antibody
    • WW C2 and coiled-coil domain containing 1 antibody
    • WW domain-containing protein 1 antibody
    • WWC1 antibody
    see all

Images

  • All lanes : Anti-KIBRA antibody (ab216508) at 1/1000 dilution

    Lane 1 : Siha cell lysates
    Lane 2 : A431 cell lysates
    Lane 3 : MCF-7 cell lysates
    Lane 4 : U2OS cell lysates

    Secondary
    All lanes : Conjugated secondary antibody at 1/20000 dilution
  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat kidney tissue labeling KIBRA with ab216508 1/200 dilution, followed by secondary antibody detection and DAB staining.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat brain tissue labeling KIBRA with ab216508 1/200 dilution, followed by secondary antibody detection and DAB staining.

References

ab216508 has not yet been referenced specifically in any publications.

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