Overview

  • Product name

  • Description

    Rabbit polyclonal to KIF13A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human KIF13A aa 1700-1800. The exact sequence is proprietary. The selected peptide was post-synthetically modified to achieve highest antigenicity before coupling to carrier protein using hetero bifunctional cross linker for Immunogen preparation. (NP_071396).
    Database link: Q9H1H9

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Antibody stabilization buffer.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab188491 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Predicted molecular weight: 202 kDa.
ELISA 1/500.

Target

  • Function

    Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.
  • Tissue specificity

    Widely expressed, with highest levels in heart, brain and skeletal muscle.
  • Sequence similarities

    Belongs to the kinesin-like protein family.
    Contains 1 FHA domain.
    Contains 1 kinesin-motor domain.
  • Developmental stage

    Expressed at very low level in most fetal tissues, but at higher levels in skeletal muscle and lung.
  • Cellular localization

    Cytoplasm > cytoskeleton > centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Recruited to the midbody during cytokinesis.
  • Information by UniProt
  • Database links

  • Alternative names

    • bA500C11.2 antibody
    • FLJ27232 antibody
    • Homolog of mouse KIF13A mannose 6 phosphate receptor transporter antibody
    • KI13A_HUMAN antibody
    • KIF 13A antibody
    • Kif13a antibody
    • Kinesin family member 13A antibody
    • Kinesin like protein KIF13A antibody
    • Kinesin like protein RBKIN antibody
    • Kinesin-like protein KIF13A antibody
    • Kinesin-like protein RBKIN antibody
    • RBKIN antibody
    see all

References

ab188491 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab188491.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up